Which One Should I Choose, Xeomin or Botox?


Xeomin is a temperature-stable botulinum toxin type A injection whose proven effectivity and stability parallels that of Botox.

Botox maintains an unprecedented track record as the most in-demand non-surgical, skin rejuvenation procedure. It has paved the way for the cosmetic usage of botulinum toxins as a stable and effective solution to eliminate signs of aging.

Botulinum toxin type A injections have been extensively proven to treat moderate to severe lines, wrinkles, and folds. Several reputable brands have emerged to provide more options for achieving the same radiant, youthful appearance, including Xeomin.

Xeomin is on a rapid rise to become as equally noteworthy as Botox. Aside from being the secret of several A-List celebrities, Xeomin is taking its own spot because of its visible effectivity, stability, and neatness in achieving flawless results.

What is Xeomin?

Xeomin is the brand name of incobotulinumtoxinA, a neurotoxin injectable used to smoothen fine lines, wrinkles, and folds caused by repetitive muscle movements. Xeomin is manufactured by Merz Pharmaceuticals and was approved by the Food and Drug Administration in 2010.

Xeomin treats the 11 glabellar lines between the brows and frown lines. It also lessens forehead creases and crow’s feet around the eyes. Aside from its cosmetic applications, Xeomin also treats cervical dystonia, blepharospasm, and limb spasticity.

Unlike any other botulinum toxins such as Botox, Xeomin does not contain any additive proteins. Xeomin is made up purely of incobotulinum toxin A molecules.

The lack of additive proteins makes Xeomin the most stable botulinum toxin type A, such that it doesn’t need any strict storage conditions. Its pure formula can survive at room temperature without any effects on its chemical formulation and balance.

Xeomin vs Botox

Like Botox, Xeomin works by paralyzing and smoothening the muscles responsible for wrinkles and folds.

The main difference between Xeomin and Botox is that Xeomin is not bounded by any complexing, accessory proteins. The only ingredient in Xeomin is botulinum toxin A. Because of this, Xeomin is considered as a pure-form injectable.

Botox requires strict storage conditions and a temperature of 2°C to 8°C to preserve product integrity.  Xeomin, on the other hand, can survive an impressive range of temperatures from 25°C to 40°C without the need for refrigeration.

There are subtle, minor differences in the way Xeomin and Botox are chemically processed, but this has not resulted in any difference in product effectivity.

Xeomin and Botox diffuse through the skin’s tissues differently, with Botox having to wear away its protective proteins before achieving full effectivity. With Xeomin, having no carrier proteins means the product is absorbed almost immediately after injection. Being heavier because of its accessory proteins, Botox molecules migrate slower in the body than Xeomin.

The pure formulation of Xeomin is scientifically considered to be more convenient to the body since the lack of complex carrier proteins prevents antibody formation or resistance to neuromuscular treatments with botulinum type A toxins. Patients who developmtolerance towards Botox may explore Xeomin as their treatment of choice.

Both Xeomin and Botox exhibit their full effects in 7 days and lasts anywhere from three to four months.

Xeomin Results and Reviews

Despite being relatively new on the market, many patients have flocked towards Xeomin injections because of its advantages over Botox. Many patients account the pure formulation of Xeomin as the factor responsible for a more subtle, effortless effect than Botox.

Xeomin is extremely similar to Botox in terms of onset and duration of action, so patients who have had both treatments cannot distinguish any differences between the two. This speaks volumes of the efficacy of Xeomin in eliminating visible signs of aging.

Final Verdict: Which Treatment Is Best for You?

Xeomin and Botox are essentially made of the same toxin, so it isn’t a surprise that both products are effectively the same.

While Botox has the upper hand in terms of popularity and reputation, Xeomin is a highly effective and stable alternative that can achieve the same optimum results.

Xeomin presents an advantage in terms of antibody formulation, which means the body is more likely to accept Xeomin more welcomingly than Botox with its complex, accessory proteins. There are fewer reactions that come with Xeomin’s pure botulinum toxin A.

Every individual has different responses to every treatment, and the decision on which treatment is better will always come from your personal experience.

The most important consideration would be choosing an experienced and board-certified healthcare provider to administer the procedure, to make sure you are receiving the treatment in its best and safest form.

Note on articles: These articles are not endorsed by DoctorMedica nor reviewed for medical accuracy. Similarly, views and opinions expressed are those of the author only. Articles are meant for informational purposes only. Ask your doctor for professional medical advice.