Radiesse Vs. Juvederm Voluma Dermal Fillers: What’s The Difference?

Radiesse vs Voluma

Radiesse and Juvederm Voluma are two highly-popular injectable dermal fillers that aesthetic professionals often seek to buy online. While both of them are used to reduce signs of aging in a non-surgical and non-invasive way, there are several important differences worth noting when picking a dermal filler for your treatments.


The main difference between these two fillers hides in their formulations as they are made of completely different ingredients.

Radiesse contains tiny microspheres of calcium hydroxylapatite (CaHA), which is found naturally within the body, primarily in bones. Unlike other dermal fillers, Radiesse not only provides the instant plumping effect upon injection but gives results that improve gradually over time as the calcium hydroxylapatite microspheres prompt the body to produce more collagen. Radiesse is FDA-approved for the correction of deep facial wrinkles and folds.

Voluma is a dermal filler that is part of the Juvederm brand of hyaluronic acid fillers. Voluma is specially designed for high-volume facial restoration and is much longer lasting than many of the other hyaluronic acid-based fillers currently available on the market. Juvederm Voluma’s intense volumizing ability, as well as its durability, is due to its unique Vycross Technology. Voluma’s Vycross Technology combines high and low molecular weight hyaluronic acid to create more efficiently cross-linked chains, making the filler smoother, easier to inject, and more resistant to degradation. It is Voluma’s Vycross Technology that creates such long-lasting results compared to other hyaluronic acid fillers. Voluma is FDA-approved for restoring volume within the face.

Treatment areas

Despite being similar in their effects, Radiesse and Juvederm Voluma fillers are used to treat different parts of a client’s face.

Radiesse can address a number of facial issues caused by age. It is not only indicated for the treatment of deep facial wrinkles and folds around the nose and mouth, but it is also able to restore volume lost due to facial lipoatrophy. Radiesse can help diminish the appearance of wrinkles, such as:

  • Nasolabial folds. Sometimes referred to as smile lines, these are the lines that start at the corners of the nose and descend outward to the corners of the mouth.
  • Marionette lines. These are the lines that begin at the corners of the mouth and descend straight down the chin.
  • Crow’s feet. These are wrinkles in the corners of the eyes that get more visible when smiling.

The volume restoring properties of Radiesse also make it a great filler for performing non-surgical augmentation in many parts of the face. It can help define the facial contour and correct asymmetries. These non-surgical procedures include:

  • Chin augmentation;
  • Cheek augmentation;
  • Rhinoplasty;
  • Jawline sculpting.

Juvederm Voluma, in its turn, is specially designed to treat volume loss in the mid-face due to the process of aging. By restoring cheek volume, Voluma is able to offer subtle lifting and improvement of the facial contours, adding more definition to the cheek area. This can help restore a more youthful appearance to patients whose mid-face area may have suffered sagging or loss of plumpness. Voluma’s formulation ensures that results are natural-looking, as the gel integrates smoothly in the mid-face area, successfully creating a smoother contour that can balance out the overall look of the face.


Both Radiesse and Juvederm Voluma fillers provide long lasting results, especially when compared with many other dermal fillers available on the market. However, Voluma can stay there up to twice as long as Radiesse, with results lasting up to two years, while patients can expect treatment with Radiesse to last anywhere from nine to 18 months. Results for both fillers will vary by patient depending on the injection technique used, the severity of the correction, and the age and lifestyle of the patient. The effects of both Radiesse and Voluma can be maintained through touch-up treatments.


Juvederm Voluma tends to be a bit more pricey than Radiesse dermal filler, however, it can still be rather affordable if you buy wholesale.

Radiesse Or Juvederm Voluma — Which One To Buy?

When it comes to choosing a dermal filler for the treatments, it mainly comes to what results you want to achieve as an aesthetics practitioner, how long your patients want them to last, and what their (and your) budget is. Both Radiesse and Voluma cosmetic fillers are great, FDA-approved, and available to buy online at DoctorMedica.

Note on articles: These articles are not endorsed by DoctorMedica nor reviewed for medical accuracy. Similarly, views and opinions expressed are those of the author only. Articles are meant for informational purposes only. Ask your doctor for professional medical advice.