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About Restylane Dermal Fillers

Restylane is a type of injectable dermal filler designed to correct facial wrinkles or folds and increase the fullness in lips. The restylane filler is in gel form and contains the active ingredient hyaluronic acid (HA) a naturally occurring substance in the body, which keeps the skin plump, supple, and hydrated. The production of hyaluronic acid declines with age, and it can lead to sagging, fine lines, and wrinkles. Restylane is administered by injecting non-animal stabilized hyaluronic acid (NASHA) beneath the skin’s surface to provide volume and fullness, and smoothen mid-to-deep wrinkles and folds.

What Makes A Good Candidate?

Patients aged 21 and above, who are looking for a non-invasive, temporary fix in smoothing wrinkles, filling shallow facial scars, sculpting lips, and providing volume to the skin, will benefit from Restylane dermal fillers. Generally, healthy adults can undergo restylane injections, as long as they are not allergic to lidocaine containing substances and hyaluronic acid based products.

This is not recommended for people with bleeding disorders, active skin infections, and multiple connective tissues diseases.1

Low Risk and Vegan Friendly

Because the hyaluronic acid in Restylane is not derived from an animal source, allergic reaction and the risk of acquiring transmissible diseases are rare.

Areas Treated with Restylane

  • Under eye wrinkles and Tear trough deformity - patients with tear trough deformity can benefit from HA dermal filler as long as overcorrection is avoided.2
  • Nasolabial folds - restylane is effective in filling deep folds, including the nasolabial folds or bracket lines 3 - the lines that run from the corner of the nose to the corner of the mouth.
  • Hollow cheeks - is a ‘sunken in face’ look that can be treated with restylane to generate volume and create a lifting effect for sagging skin.
  • Thinning lips - restylane is indicated in submucosal implantation for lip augmentation.
  • Marionette lines - depletion of facial volume causes these deep creases to appear below the mouth. Injectable fillers, in addition to Botox, is one of the mainstay treatments for these.
  • Skin lacking firmness and elasticity - HA fillers boost the hydration levels in deep layers of the skin, improving the skin’s firmness and elasticity.

 

How Does Restylane Work?

Hyaluronic acid (HA), also known as hyaluronan, is the active ingredient in restylane dermal fillers. The FDA-approved substance is biodegradable and exhibits no species and tissue specificity. This means allergic reaction and transplantation rejection rarely occur with NASHA, making restylane a safe and stable treatment for wrinkles.

Once injected, the hydrophilic (water-loving) hyaluronic acid binds to water molecules, causing the underlying tissue to look plumper and more youthful looking. Restylane injection creates a gel swelling that can withstand compressive forces, so results can be seen immediately. It gradually disintegrates in the body leaving no residue.

 

Treatment Details

The procedure is performed in the doctor's office for patients over the age of 21. Skin or allergy test is not required for restylane injection because it contains a natural form of hyaluronic acid compared to the animal-derived substances used in the past. It is often administered with lidocaine or local anesthesia, especially if the injection site is on the lips or around the mouth.

The doctor may first choose one or more injection points for each site being treated. An antiseptic will first be applied, and the dermal filler will be injected beneath the skin. The whole procedure may last up to half an hour. Your patient can go home immediately after the procedure.

Wondering how soon can your patients see results?

The results will be fully visible within a couple of weeks. The whole procedure may last up to half an hour. Your patient can go home immediately after the procedure.

How Long Does Restylane Last?

Hyaluronic acid fillers can last for six to nine months. The effect of restylane depends on the area being treated, the amount of substance administered, and the metabolism of the individual. It tends to last longer in areas that are least mobile. It diminishes rapidly in areas that are most mobile, such as the lips.

Safety Information

Although it is generally safe and effective to undergo dermal filler injections, it can still pose some risks to other people. Swelling has been reported to last for two to three days. Some patients also reported experiencing headache, nausea, redness, and pain at the site of injection. Your doctor will discuss with you the possible complications and remedies of undergoing HA injection. Follow up treatment sessions are recommended to achieve better, long-lasting results.

Other possible side effects:

  • Tenderness
  • Itching
  • Nodule formation
  • Scabbing on the affected area
  • Pain and soreness

Recovery Time

Your patients may experience pronounced swelling in the affected area that may last for up to three days. Although normal activities can be resumed after the procedure, it is strongly advised to avoid sun exposure. HA dermal fillers can diminish fine lines and wrinkles for up to 80 percent. Tell your patients to consult you immediately if they experience extreme pain, and other negative symptoms that do not go away.

Cost of Restylane

Patients can expect a single syringe of Restylane to cost between $300 - $800 in the USA. A second injection may be administered after six months. Negative effects become less prominent for subsequent injections. Opting for restylane fillers is cheaper than fat grafting but the latter may last longer.


References:

De Boulle, K., & Heydenrych, I. (2015). Patient factors influencing dermal filler complications: prevention, assessment, and treatment. Clinical, Cosmetic and Investigational Dermatology, 8, 205–214. http://doi.org/10.2147/CCID.S80446

Gold, M. H. (2007). Use of hyaluronic acid fillers for the treatment of the aging face. Clinical Interventions in Aging, 2(3), 369–376.

Baumann, L. S., Shamban, A. T., Lupo, M. P., Monheit, G. D., Thomas, J. A., Murphy, D. K., & Walker, P. S. (2007). Comparison of Smooth-Gel Hyaluronic Acid Dermal Fillers with Cross-linked Bovine Collagen: A Multicenter, Double-Masked, Randomized, Within-Subject Study. Dermatologic Surgery, 33. doi:10.1111/j.1524-4725.2007.33352.x



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