Manufacturer : Anika Therapeutics

Active Substance(s) : Sodium hyaluronate

Pack Size : 1-4ml prefilled syringe

Accessories : Package insert, 1 traceability label


$249.00 / unit

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Add 5 more units to your cart and save $60.00.
Quantity Our Price
1 - 5 pack(s) $249.00 USD
6 - 10 pack(s) $239.00 USD
11 - 20 pack(s) $234.00 USD
21+ pack(s) USD$229.00 229.00USD

Product Information

Where can I get this product?

Cingal is a medication for the treatment of knee osteoarthritis, and you can purchase it online or by phone from Order wholesale Cingal from Doctor Medica to ameliorate OA-related knee pain for your patients.

Product Information

What does this product come with?

Cingal is supplied in a 5ml prefilled syringe that contains a 4ml dose of this viscosupplement. The supplied Cingal is sterile and non-pyrogenic. The syringe components are free of latex.

What are the benefits of this product?

With a Cingal injection, a patient gets rapid and long-lasting pain relief from their osteoarthritis, allowing for an improvement in their quality of life. As a single-dose regimen, Cingal is fast, easy, and convenient to administer.

What is this product made of?

This product is made of 88mg of sodium hyaluronate, 18mg of triamcinolone hexacetonide, 200 mg of sorbitol, 8mg of polysorbate 80, 6mg of dibasic sodium phosphate, 1.2mg of monobasic sodium phosphate, and 4ml of USP water for injection q.s.

How does this work to help my patients?

Osteoarthritis is a degenerative disease of the joints that results in symptoms of pain, swelling, and inflammation. It severely restricts movement and affects the quality of life of the afflicted. Osteoarthritis’s symptoms arise from the breakdown of cartilage at the ends of bones, resulting in painful, inflamed joints. Joints are enclosed in a capsule that contains a thick, slippery substance known as synovial fluid. Synovial fluid is responsible for lubricating joints and absorbing shock so as to prevent the deterioration of the cartilage from wear and tear. In diseased individuals, there is less synovial fluid in joints and the main component of this fluid—hyaluronic acid—is altered in its composition, leading to the synovial fluid becoming less viscous and losing the viscoelastic properties that make it work properly.

Cingal is unique because it combines hyaluronan and a corticosteroid, which are both used to assuage pain related to osteoarthritis in the knee. Cingal’s hyaluronic acid content is high molecular weight and highly modified hyaluronan that has similar viscoelastic properties to healthy synovial fluid. When Cingal is injected, its hyaluronic acid helps to supplement the synovial fluid available in the diseased joint. The other medication, triamcinolone hexacetonide, is a steroid that provides short-term pain relief by reducing joint inflammation.

Use Instructions

How do I use this product?  

Cingal is administered as a single intra-articular injection into the affected knee joint.  Before the injection, the injection site should be prepared according to standard guidelines. Not only that, strict aseptic standards should be adhered to throughout the procedure. Before injecting Cingal, joint effusion should be removed using an 18–20 gauge needle. Separate syringes should be used to remove effusion and to inject Cingal, but the same 18-20 gauge needle can be used. The protective rubber cap on the tip of the prefilled Cingal syringe should be removed, and a needle should be attached to the tip. The needle should be secured tightly but not overtightened. Also, do not apply excessive leverage onto this needle, as this may break the syringe tip. The full 4 ml dose of the prefilled syringe should be injected in one knee only without overfilling the joint. Use a separate syringe if treatment is needed for the other knee.    

How long will the treatment take?

Cingal is a single-dose treatment and given as an intra-articular injection into the synovial cavity.

What can I use it for?

Cingal is used for the management of pain that comes with knee osteoarthritis. Patients should use this medication after other first-line treatments for osteoarthritis, such as simple analgesics and non-pharmacological therapy, have not produced the desired level of pain relief.

What areas should I use this product on?

Cingal is administered to the intra-articular cavity in the knee joint.

How long do the results last?

Patients can experience pain relief as soon as 24 hours after administration. The benefits of Cingal have been shown to last up to six months.

Frequently Asked Questions

Why should I use this product?

Cingal is a unique knee medication that combines the rapid onset of steroids with the long-lasting duration of hyaluronan to provide fast-acting and enduring relief medication for the management of pain that comes with osteoarthritis in the knee.

Who is this product intended for?

This medication is given to treat the joint pain experienced by patients with knee osteoarthritis. This medication can be considered once other standard therapies for osteoarthritis, including physical therapy and pain medications, have failed to produce sufficient pain relief. Patients who are allergic to hyaluronan, triamcinolone hexacetonide, or the other ingredients in this medication; patients with skin diseases or infections at the injection site; and pregnant or lactating women should not receive Cingal therapy.

What are the side effects?

The potential side effects of Cingal include arthralgia; local swelling; effusion; stiffness of the knee; arthropathy; injection site pain, edema, bruising, and/or erythema; facial flushing; post-injection flare; and injection site skin atrophy, calcification, or hypopigmentation. Diabetics may observe a transient increase in blood sugar. Rare side effects include infection, tendinopathy, or Nicolau’s syndrome (dermatitis).

This list of side effects is not exhaustive. Please refer to Cingal’s package insert for a complete list of contraindications, precautions, and possible side effects.

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