Belotero vs. Juvederm: Key Differences

Dermal Fillers


Last Updated On: 2024-01-25

Discover shared traits in Belotero and Juvederm: both harness HA to restore volume and reduce wrinkles effectively.

Doctor Medica team

Dermal fillers are essential in facial rejuvenation, helping patients achieve a youthful and refreshed appearance. With the wide range of dermal fillers available, aesthetic doctors must thoroughly know their characteristics and choose the most appropriate filler for each patient’s unique needs.

The choice of dermal filler depends on several factors, including the specific concerns of the patient, the desired outcome, and the injector’s expertise. So, selecting a filler that addresses the patient’s aesthetic goals and the same time, fits the concern perfectly and ensures natural-looking results and minimal side effects is crucial.

What Is Belotero?

Belotero is a brand of hyaluronic acid-based dermal fillers offering a range of formulations with different textures to address various beauty concerns. One of its key advantages is integrating seamlessly into the skin, providing natural-looking results. Belotero is particularly suitable for treating fine lines, superficial wrinkles, and delicate areas such as the lips and tear troughs.

The most popular Belotero formulations include Belotero Soft, Belotero Balance, Belotero Intense, and Belotero Volume. Each solution targets specific depths and areas of the face, allowing for precise and tailored treatments. 

Belotero Soft Contains only 20% hyaluronate and is used to eliminate small wrinkles, so it is injected only into the top layer of the skin. Belotero Balance is ideal for smoothing superficial lines, while Belotero Intense is suitable for deeper wrinkles and folds. Belotero Volume is designed to restore lost volume in areas such as the cheeks and temples.

In terms of longevity, the duration of Belotero’s effects varies depending on the specific formulation used and individual factors. Generally, results can last between six to twelve months. However, it is essential to note that individual responses may vary.

What Is Juvederm?

Juvederm is another well-known hyaluronic acid-based dermal filler brand with a range of formulations to address various aesthetic problems. It is known for its smooth consistency, allowing easy injection and natural-looking results. Juvederm is commonly used to restore volume, fill deep wrinkles and folds, and enhance lip contours.

The main products of the Juvederm line include Juvederm Ultra, Juvederm Ultra Plus, Juvederm Volift, and Juvederm Voluma.

Juvederm Ultra is suitable for correcting moderate to severe facial wrinkles and folds, while Juvederm Ultra Plus is designed for deeper lines and folds.

Juvederm Voluma is formulated to restore volume in the mid-face region, such as the cheeks and chin. Juvederm Volift is an update to the Volbella line of products used to fill voids under nasolabial folds.

The duration of Juvederm’s effects also varies depending on the specific formulation used and individual factors. Results typically last between nine and twelve months, providing patients with long-lasting outcomes. However, unique variations in metabolism and lifestyle factors in different patients can influence the duration of the results.

Comparing Belotero vs. Juvederm

Belotero and Juvederm share similarities in their primary ingredient (HA), mode of action, and ability to restore volume and also reduce the appearance of wrinkles. However, several key differences set them apart, making them suitable for different treatment areas and patient profiles.

Similarities Between Belotero and Juvederm

  1. Both Juvederm and Belotero are soft, gelatinous dermal injectables with hyaluronic acid bases.
  1. Those brands’ products provide non-surgical, minimally invasive treatments that offer patients the benefits of facial rejuvenation without surgery.
  1. Belotero and Juvederm provide temporary results, allowing patients the flexibility to adjust or reverse the effects if desired.
  1. Both brands have products with lidocaine hydrochloride to minimize the pain level and possible discomfort a patient might feel during injections.
  1. These injectables have similar indications and contraindications.
  1. Like any dermal filler, Belotero and Juvederm have potential side effects like redness, swelling, or bruising at the injection site. However, these are typically mild and temporary. Aesthetic doctors should be aware of any specific considerations when using those injectables, such as cautiously treating patients with a history of severe allergies or autoimmune disorders.

Differences Between Juvederm and Belotero

  1. Significant distinctions between Belotero and Juvederm can be made in their texture and cohesiveness. 

Belotero is known for its softer and more flexible texture, allowing for seamless integration into the skin. This property makes it an excellent choice for treating superficial lines and delicate areas with precision.

On the other hand, Juvederm has a smooth consistency that provides structure and support, making it suitable for addressing deeper wrinkles and folds and volumizing larger areas.

  1. The depth of injection is another difference between Belotero and Juvederm.

Belotero’s different formulations cater to specific depths, enabling doctors to choose the most appropriate product for each area of concern. This precision is particularly advantageous when treating fine lines and delicate areas like the lips. 

With its range of formulations, Juvederm allows for more versatility in addressing moderate to severe wrinkles, deep folds, and volume loss in various facial regions.

  1. The longevity of results is an important aspect when comparing dermal fillers.

While both Belotero and Juvederm provide relatively long-lasting outcomes, the specific formulation used and individual patient factors can influence the duration of results. Typically, Juvederm may offer slightly longer-lasting effects than Belotero, with results lasting up to 12 months or more in some cases.

  1. Patient comfort is another aspect to consider when comparing Belotero and Juvederm. Belotero’s soft and flexible texture may offer enhanced comfort during injection, particularly in sensitive areas. 

Juvederm’s smooth consistency allows for easy and controlled administration, ensuring a comfortable experience for patients as well.

Choosing The Right Dermal Filler

Selecting the most appropriate dermal filler for each patient requires a comprehensive evaluation of their needs, concerns, and desired outcomes. Factors like patient age, skin type, treatment area, and the depth of correction required should all be considered.

For patients seeking treatments for fine lines, superficial wrinkles, or delicate areas like the lips or tear troughs, Belotero may be preferred due to its softer texture and precise application. On the other hand, Juvederm’s versatility and ability to address deeper wrinkles, folds, and volume loss make it suitable for a broader range of facial rejuvenation procedures.


Belotero and Juvederm are both popular dermal fillers that offer effective solutions for facial rejuvenation. While they share many similarities, both being hyaluronic acid-based fillers, they also have distinct characteristics that make them suitable for different treatment areas and patient profiles.

Aesthetic doctors should continually update their knowledge and expertise on dermal fillers, including updates on Belotero and Juvederm, to provide the most advanced and suitable treatments for their patients. By understanding each filler’s unique characteristics and properties, doctors can select the most appropriate option to meet their patients’ specific goals and expectations, ensuring safe and satisfying outcomes in aesthetic medicine.


Is Juvederm better than Belotero?

The question of which is better, Belotero or Juvederm, is subjective and depends on various factors. Juvederm and Belotero are both highly regarded hyaluronic acid-based dermal fillers widely used in aesthetic medicine.

The choice between them ultimately depends on the patient’s needs and goals and the aesthetic doctor’s expertise and preference. Here are some considerations to keep in mind:

Belotero, known for its low density, is well-suited for addressing fine lines and wrinkles. It is injected into the superficial layers of the skin or the upper section of the dermis and is commonly used to target very fine lines, enhance cheekbones, treat delicate areas like the lips and tear troughs, and improve overall facial contouring.

In contrast, Juvederm fillers have a higher density and are injected deeper into the skin. This dense formulation makes Juvederm beneficial for treating moderate to severe wrinkles and deep folds and volumizing larger areas like the cheeks and chin. By targeting these deeper layers, Juvederm fillers can provide more substantial wrinkle reduction, facial volumization, and contour enhancement results.

Ultimately, both Juvederm and Belotero have their strengths and are widely used and respected in the aesthetic field. The decision of which filler, Juvederm or Belotero, is better for a particular case should be based on a thorough consultation and a personalized treatment plan.


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Kapoor KM, Saputra DI, Porter CE, Colucci L, Stone C, Brenninkmeijer EEA, Sloane J, Sayed K, Winaya KK, Bertossi D. Treating Aging Changes of Facial Anatomical Layers with Hyaluronic Acid Fillers. Clin Cosmet Investig Dermatol. 2021 Aug 26;14:1105-1118. doi: 10.2147/CCID.S294812. PMID: 34471372; PMCID: PMC8405095.

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Kleine-Börger, L., Meyer, R., Kalies, A., & Kerscher, M. (2022). Approach to differentiate between hyaluronic acid skin quality boosters and fillers based on their physicochemical properties. Journal of Cosmetic Dermatology, 21(1), 149-157.

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