Orthovisc Injection for Knee Osteoarthritis: How It Works and What to Expect

A 2021 study highlighted the enduring benefits of non-animal stabilized hyaluronic acid (HA) injections for knee osteoarthritis. The study demonstrated that patients enjoyed pain relief for an average of 467 days following the initial treatment. This significant relief duration underscores the potential of HA injections as a long-term management strategy for osteoarthritis symptoms.

Orthovisc distinguishes itself from other viscosupplement treatments by using high molecular weight HA in its formulation. It copies the viscoelastic properties of healthy joint fluid, restoring natural joint balance and providing sustained pain relief for those unsatisfied with the results from similar treatments.

In this article, we will explore the inner workings of Orthovisc injections. We’ll delve into how they function, the typical injection process, and what to expect after the procedure, giving you a comprehensive understanding of this treatment option.

Key Takeaways

• Orthovisc injections are a viscosupplement therapy designed to lubricate and cushion the joints, particularly in individuals with knee osteoarthritis.
• The treatment involves injecting a gel-like substance containing hyaluronic acid, a naturally occurring sugar molecule found in the synovial fluid of the joints, directly into the knee joint space.
• Clinical studies have demonstrated the efficacy of Orthovisc injections in providing symptomatic relief for patients with knee osteoarthritis.
• The treatment process for Orthovisc injections is relatively straightforward, with minimal discomfort and downtime.
• Following Orthovisc therapy, individuals can expect significant reductions in knee pain and stiffness and improvements in joint function and mobility.

What Are Orthovisc Injections?

Orthovisc injections are a form of viscosupplementation treatment that relieves knee pain caused by osteoarthritis. The main ingredient is hyaluronic acid (HA), similar to the fluid that naturally surrounds the joints in the body. 

Once injected, Orthovisc treatments act as lubricants and shock absorbers for the joints. The injection aims to replace the lost HA and improve the quality of the remaining synovial fluid, reducing pain and improving a patient’s joint function. Healthcare professionals usually prescribe this treatment after other medications for arthritis have not been successful. 

How Orthovisc Injections Differ from Other Knee Osteoarthritis Treatments

Orthovisc injections are used for treating knee osteoarthritis without the hassle of surgery, offering a different approach than other standard treatments. Here’s how they compare:

• Orthovisc Injections: This treatment involves injecting hyaluronic acid directly into the knee joint to restore the joint fluid’s cushioning and lubricating properties. The effects can last up to 26 weeks.
• Corticosteroid Injections: Corticosteroids are anti-inflammatory medications that can reduce pain and swelling once injected. The relief they provide is generally shorter than Orthovisc, and repeated injections may lead to side effects like osteoporosis of nearby bone tissue.
• Physical Therapy: Physical therapy includes exercises and manual therapy to strengthen the muscles around the knee, improve flexibility, and reduce pain. While it doesn’t directly treat joint fluid like Orthovisc, it can help manage symptoms and improve function over time.
• Oral Medications: These systemic treatments can include pain relievers like acetaminophen or anti-inflammatory drugs like NSAIDs. They can help manage pain but do not have the same targeted action within the knee joint as Orthovisc injections.
• Surgical Intervention (e.g., Knee Surgery): Experts consider this treatment option for osteoarthritis when other treatments have failed to provide relief. It can range from arthroscopic procedures to partial or total knee replacements. In contrast, knee replacement surgery involves replacing damaged parts of the knee with artificial components and is a more invasive option with a more extended recovery period.

Efficacy of Orthovisc Injections for Knee Osteoarthritis

When it first came out, many patients and professionals asked, “Does Orthovisc really work?” or “Is it really effective for osteoarthritis?” Because of these questions, Orthovisc injections have been evaluated in various clinical studies to determine their effectiveness in treating knee osteoarthritis and providing long-lasting pain relief for the joints.

The U.S. Food and Drug Administration (FDA) has approved Orthovisc based on safety and effectiveness data, indicating its use for pain relief in patients who have not responded adequately to conservative non-pharmacologic therapy and simple analgesics.

A 2006 Cochrane Review, a highly respected source of medical evidence, analyzed 76 randomized controlled trials on the use of hyaluronic acid injections for knee OA. The review found some evidence suggesting that hyaluronic acid injections, including Orthovisc, may be beneficial for pain, physical function, and overall improvement compared to a placebo. The most substantial effects appeared between 5 and 13 weeks after injection.

Clinical trials have shown that Orthovisc provides pain relief compared to saline placebo injections. A systematic review and meta-analysis published in The BMJ also evaluated the effectiveness of viscosupplementation, like Orthovisc, for pain and function in patients with knee osteoarthritis. The study found that viscosupplementation could significantly reduce pain intensity and improve function.

Long-Term Benefits of Orthovisc Injections for Knee Osteoarthritis Patients

• Pain Relief: Some studies suggest that Orthovisc injections provide pain relief lasting several months, potentially up to 6 months.
• Functional Improvement: Studies have also shown and proven that Orthovisc injections can improve joint function and mobility, allowing patients to participate more actively in daily activities.
• The Durability of Effects: The long-term durability of the benefits from Orthovisc injections varies. Some patients may experience sustained improvement, while others may require repeated injections.
• Potential to Delay Surgery: Real-world evidence suggests that patients who receive hyaluronic acid (HA) treatments like Orthovisc can avoid getting surgery for their knee for up to an average of 3.6 years. This advantage allows healthcare professionals to integrate Orthovisc as a valuable part of a long-term management strategy for knee osteoarthritis.

It’s crucial to discuss the potential benefits and risks of Orthovisc injections with your doctor to determine if they are a suitable treatment option for your case. If you’re considering Orthovisc injections, it’s wise to ask your doctor about the specific type of hyaluronic acid used, the expected benefit duration, and the potential need for repeat injections. 

The Orthovisc Treatment Process

The Orthovisc treatment process typically involves several steps, including a vital consultation before any similar procedure. During an initial consultation, your doctor will discuss your medical history, symptoms, and X-rays or other imaging tests to diagnose knee osteoarthritis and determine if Orthovisc injections are a suitable treatment option.

Before the injections, your doctor might assess your knee joint for swelling, tenderness, or range of motion. They may also discuss the potential risks and benefits of the injections and obtain your informed consent. The healthcare professional may begin preparing the knee for the injections following this step.

Injection Procedure

The treatment typically involves a series of injections directly into the knee joint, administered by a qualified healthcare provider. Here’s a breakdown of what to expect:

• The area around your knee will be cleaned and sterilized.
• Your doctor injects Orthovisc directly into the knee joint using a sterile needle. They may use image guidance, such as ultrasound or fluoroscopy, to ensure accurate placement.
• After the procedure, your doctor may bandage the injection site to avoid infection and help the hyaluronic acid settle between your joints.

Potential Side Effects and Risks Associated with the Treatment

While Orthovisc injections are generally safe, they can be associated with specific side effects and risks.  Here’s what patients and medical practitioners should be aware of:

• Pain and Swelling: Mild pain, redness, and swelling at the injection site are expected and usually subside within a few days.
• Infection: There’s a small risk of infection at the injection site. Proper sterile technique during the procedure helps minimize this risk.
• Bleeding: Minor bleeding at the injection site can occur.
• Allergic Reactions: Allergic reactions to hyaluronic acid are rare but possible.

Patient Experience and Recovery After Orthovisc Injections

The journey to recovery after receiving Orthovisc injections is a personal and varied experience for patients with knee osteoarthritis. Though some patients found little to no success with Orthovisc, most of the patients who shared their outcomes from this treatment recommend it to others who are dealing with knee pain caused by osteoarthritis in their joints.

In 2019, one patient shared how Orthovisc turned their life around after battling knee pain. According to Peep from Drugs.com, they were doubtful about the effectiveness of Orthovisc at first. However, Peep decided to go through with getting Orthovisc since they couldn’t endure the concrete-like heaviness in their knees of feeling a shooting pain.

This pain came from many factors, including previous injuries to the knees, fibromyalgia, and osteoarthritis. When Peep first received Orthovisc, they shared how they felt relief in such a short amount of time. Their first round of Orthovisc treatment lasted almost three years, and Peep felt hopeful about the outcomes of their follow-up injections.

Another patient who had long-term pain relief from Orthovisc was Mare, a 72-year-old female patient who was enduring bone-on-bone osteoarthritis in the knees. In her 10/10 review, Mare shares how Orthovisc was like a miracle for them. For three years, Orthovisc helped her manage the pain that came with this degenerative joint disease.

Expected Recovery Timeline and Post-injection Care Instructions

The recovery timeline after Orthovisc injections can vary from patient to patient, but generally, the treatment involves a series of three injections administered weekly. Patients may start to feel pain relief shortly after the first injection, but it is common for the full benefits to be more noticeable after the complete series of injections.

It’s also vital to follow specific care instructions to ensure the best possible outcome and minimize any potential side effects. Here are some guidelines for post-injection care:

• Keep the Injection Site Dry: Maintain a clean bandage over the injection site for 24 hours following the procedure.
• Avoid Water Immersion: Do not bathe, use a hot tub or sauna, go swimming, or submerge the treated area in water for two days after the injection.
• Manage Soreness: The injection site may be sore for a few days. It’s advisable to consult with your doctor about taking pain medication if necessary.
• Apply Ice and Heat: For the first 24 hours, you may apply ice (wrapped in a cloth) to the site for 20 minutes on and then 20 minutes off to decrease pain. After 24 hours, you may use heat if needed.
• Activity Restrictions: Ask your doctor if there are any activities or movements that you should avoid, such as standing for long periods, jogging, or lifting heavy objects.
• Medication Continuation: Keep taking your prescribed pain medicine as directed by your healthcare provider.

Lifestyle Modifications After the Treatment

After receiving Orthovisc injections for knee osteoarthritis, patients should make certain lifestyle modifications and be mindful of activities that could affect the knee’s recovery and overall joint health. Here’s a detailed look at the recommendations:

• Weight Management: Maintaining a healthy weight can reduce stress on the knee joints.
• Balanced Diet: A diet rich in anti-inflammatory foods may help manage osteoarthritis symptoms.
• Hydration: Adequate fluid intake is essential for maintaining the elasticity of joint cartilage.
• Exercise: Low-impact exercises such as swimming, cycling, or walking can help strengthen the muscles around the knee without putting excessive pressure on it.

For at least 48 hours post-injection, avoid strenuous activities like jogging, tennis, or high-impact sports. Refrain from lifting heavy objects, as they can put undue stress on the knee joint. You should also avoid standing for more than one hour at a time to prevent additional strain on the knees.

Conclusion

Orthovisc injections present a viable option for those battling knee osteoarthritis, aiming to alleviate pain and enhance life quality. Gaining insight into the mechanism of Orthovisc and the treatment journey enables patients to evaluate its suitability for their condition carefully. It’s crucial for patients to actively engage with healthcare professionals to determine if Orthovisc is an appropriate choice for their osteoarthritis management.

About: DoctorMedica is your trusted supplier of top-quality dermal fillers, viscosupplements, and more for your medical practice. We offer genuine products from leading brands at the lowest prices in the market. Whether you need a specific product or various options, we can help you find the best deals for your needs. Plus, you can enjoy our promotions and free shipping for orders over $500. With DoctorMedica, you can offer your patients the best results for less.

FAQs

1. How does Orthovisc work?

Orthovisc works by replenishing the synovial fluid in the knee joint with hyaluronic acid, which acts as a lubricant and shock absorber, helping to reduce pain and improve joint mobility in patients with osteoarthritis.

2. How do I know I’m a good candidate for Orthovisc?

You may be a good candidate for Orthovisc if you have knee osteoarthritis and have not found adequate pain relief from conservative treatments like exercise, physical therapy, or simple analgesics such as acetaminophen.

3. Can I buy Orthovisc online?

Only licensed healthcare professionals can purchase Orthovisc from online distributors like Doctor Medica. More importantly, they should be the only ones to administer the treatment.

References

Aggarwal A, Sempowski IP. Hyaluronic acid injections for knee osteoarthritis. Systematic review of the literature. Can Fam Physician. 2004;50:249-256.

Orthovisc for osteoarthritis reviews. Drugs.com. https://www.drugs.com/comments/hyaluronan/orthovisc-for-osteoarthritis.html