Restylane: Usage, Benefits & Side Effects

Dermal Fillers


Last Updated On: 2024-01-12

The Restylane filler line offers a range of biogels tailored to different imperfections and containing additives like lidocaine.

Doctor Medica team

Contour modeling is an integral part of injectable cosmetology and is used to shape facial features in patients with various types of skin aging. For this purpose, many clinics utilize premium fillers from the Restylane brand, manufactured by Q-Med, a Swedish company within Galderma.

What Is Restylane?

Restylane is one of the most popular biogel fillers successfully used for contouring procedures. The product contains hyaluronic acid and is utilized for filling fine and deep wrinkles and folds, and for facial oval and lip contour corrections.

The Restylane filler line offers a range of biogels tailored to different imperfections and containing additives like lidocaine. Unlike its counterparts, Restylane has a dense consistency, resulting in a slower absorption in soft tissues and providing a longer-lasting effect.

How Does Restylane Work?

When injected into the skin, the gel components rapidly interact with the body’s organic tissues. Hyaluronic acid, the main component, promotes moisture accumulation and retention in the skin tissues. As a result, the skin gains the necessary volume and becomes smoother, appearing healthy and youthful. Restylane has a long-lasting effect as it stimulates hyaluronic acid production in the body.

This method is also used for correcting the shape of lips, facial contours, nose, and other areas. In addition, it is highly effective in smoothing wrinkles and addressing signs of aging.

The duration of the effect depends on the specific filler (primarily its density) and the area treated. It typically ranges from six to eighteen months but can be longer, too. Thanks to the innovative development by Q-Med experts, the biodegradation or dissipation of the product does not immediately diminish its effect. Hyaluronic acid is structured in such a way that its molecules attract, bind, and help retain water molecules, ensuring the prolonged action of each filler.

To fully utilize the potential of Restylane products, it is not enough to select a suitable filler. A flawless injection technique is crucial, requiring a high level of expertise from the cosmetologist. This minimizes the risk of side effects, guarantees a short recovery period, and ensures the best results.

Types of Restylane Filler

  1. Restylane is widely recognized as a leading choice among hyaluronic acid-based fillers for face contouring and rejuvenation. It effectively fills fine lines and wrinkles and enhances facial volume, resulting in a more youthful appearance. 
  2. Restylane Defyne is specifically designed to treat deep facial wrinkles and folds. It provides natural-looking results by supporting the skin’s structure and maintaining facial expressions. It is ideal for targeting nasolabial folds and marionette lines.
  3. Restylane Kysse is a lip filler designed to enhance the lips’ volume and shape. It provides a soft, natural feel and can help achieve a more balanced and appealing lip appearance.
  4. Restylane Lyft is a versatile filler that addresses volume loss in various facial areas, including cheeks, temples, and the midface. It can restore youthful contours and improve the appearance of sagging skin, resulting in a more lifted and rejuvenated look.
  5. Restylane Skinboosters, which are based on Restylane Vital formulations are a unique treatment for skin hydration and rejuvenation. They improve skin quality, texture, and elasticity by delivering deep hydration, making them suitable for the face, neck, décolletage, and hands.
  6. Restylane Volyme, also known as Restylane Volume, is specifically formulated to restore volume and contour to the cheeks and chin. It provides natural-looking results by enhancing facial proportions, improving cheekbone definition, and creating a youthful appearance.

Using Restylane 

A Restylane procedure typically involves the following steps:

  1. Consultation: The patient meets with a qualified healthcare professional to discuss their concerns, desired outcomes, and medical history. The professional assesses the patient’s facial structure and determines the appropriate Restylane treatment plan.
  2. Preparation: The treatment area is thoroughly cleansed, and a topical anesthetic may be applied to numb the area and minimize discomfort during the procedure. The healthcare professional may also mark injection points to guide the placement of the filler.
  3. Injection: The healthcare professional injects Restylane into the targeted areas using a fine needle or a blunt-tipped cannula. They carefully administer the filler to create the desired contour, add volume, or fix wrinkles. Restylane injection technique may vary depending on the specific area being treated.
  4. Assessment and adjustment: After injecting the filler, the healthcare professional evaluates the results and may make additional injections or adjustments to ensure optimal outcomes. The main aim is to achieve natural-looking results and facial harmony.
  5. Post-treatment care: The patient is provided with aftercare instructions, including avoiding strenuous activities, excessive sun exposure, and certain medications or treatments. Cold compresses may be recommended to reduce swelling or bruising at the injection sites. Following the healthcare professional’s guidance is essential for the best recovery and results.

Is Restylane Safe?

RESTYLANE has received FDA approval following successful safety and efficacy studies and comparative clinical trials. Restylane is manufactured using the patented NASHA technology by Q-MED, which involves minimal stabilization of hyaluronic acid to create a dense gel. The raw materials are typically sourced through microbial fermentation of soy or wheat. Restylane is a biodegradable product that gradually breaks down and is naturally eliminated from the body over time.


The main reasons why this procedure may not be advised are:

  • Pregnancy (and lactation period);
  • Exacerbation of chronic diseases;
  • Antibiotics;
  • Blood diseases;
  • Cancer diseases;
  • Diabetes mellitus;

Benefits Of Restylane

  1. A Natural Approach: Restylane fillers mimic the natural hyaluronic acid, restoring volume to the skin and providing a supple and smooth appearance. Whether applied to the face, lips, or hands, Restylane ensures a natural and beautiful outcome.
  2. Tailored Solutions: Each Restylane product is uniquely formulated to address specific skin concerns, offering a personalized approach to meet diverse needs and achieve natural and comfortable results.
  3. Safety First: Restylane is FDA-approved and boasts an excellent safety profile with minimal risk of side effects or complications. With over 20 million treatments performed, Restylane remains one of the most trusted and reliable dermal fillers on the market.
  4. Naturally Beautiful Results: Unlike some other fillers, Restylane injections preserve facial expressions, allowing for a more authentic and natural look. It ensures that the results are seamlessly integrated with your facial dynamics.

Possible Restylane Side Effects

  • Erythema (skin redness);
  • Edema (swelling);
  • Bruising;
  • Discomfort or sensitivity;
  • Itching or irritation;
  • Temporary hyperpigmentation;
  • Formation of scabs at the injection site;
  • Rare cases of infection.


Contour modeling using Restylane fillers is a highly effective approach in injectable cosmetology for shaping facial features in patients with different types of aging. Clinics have widely embraced Restylane brand premium fillers for their ability to provide natural and beautiful results. 

The FDA has approved the safety and efficacy of Restylane, and its wide range of products allows for tailored solutions to meet individual needs. While minor side effects may occur, Restylane remains a trusted and reliable option for a natural-looking, youthful, and beautiful appearance.


Which is better, Restylane or Juvederm?

Both Restylane and Juvederm are reputable brands of hyaluronic acid-based dermal fillers. However, the choice between them depends on individual needs and preferences, and it is best to consult with a professional who can assess the patient’s specific concerns and recommend the most suitable product.

What is Restylane good for?

Restylane is a versatile dermal filler used for various aesthetic treatments. It is commonly used to enhance facial contours, reduce wrinkles and fine lines, augment lips, restore lost volume in the face, rejuvenate the hands, and perform non-surgical nose reshaping. Its hyaluronic acid-based formula provides natural-looking results and can address various cosmetic concerns.

Is Restylane better than Botox?

Restylane and Botox are different treatments with distinct mechanisms of action. Restylane is a dermal filler that adds volume and fills in wrinkles. Botox is a neurotoxin that temporarily relaxes muscles, effectively reducing the appearance of wrinkles caused by facial expressions.

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