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BOTOX®

If you want to buy BOTOX® online, our sales team can provide instructions. BOTOX® is derived from a toxin produced by the bacterium Clostridium botulinum. Allergan manufactures it and works by cleaving SNARE proteins, which prevents the fusion of acetylcholine-containing vesicles with the presynaptic membrane. This prevents acetylcholine release, inhibits muscle contraction, and makes BOTOX® a useful treatment for wrinkles, muscle spasms, migraine, and more.

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What Is BOTOX® Used For?

BOTOX® is used for both medical and cosmetic purposes. The cosmetic indications of BOTOX® include:
  • Forehead lines
  • Lateral canthal lines (also called Crow’s Feet)
  • Glabellar facial lines (also called frown lines)
Medically, BOTOX® can treat the following disorders in adult patients:
  • Overactive bladder
  • Anal sphincter disorders
  • Achalasia
  • Chronic migraine prophylaxis
  • Upper and lower limb spasticity
  • Cervical dystonia
  • Laryngeal dystonia
  • Primary axillary hyperhidrosis
  • Blepharospasm
  • Strabismus
In children, BOTOX® is used to treat strabismus, blepharospasm, and spasticity associated with cerebral palsy.

BOTOX® Contraindications

There are four main contraindications of BOTOX®:
  • Allergic reaction to any botulinum toxin product or any of its ingredients
  • Infection at the site(s) where the injection is planned
  • Injecting into the bladder muscle (intradetrusor injection) in urinary tract infection patients with overactive bladder or bladder muscle overactivity linked to a neurological condition
  • Injecting into the bladder muscle in patients with urinary retention or a post-void residual volume exceeding 200 mL who do not regularly self-catheterize.
In addition, BOTOX®’s safety and effectiveness have not been proven in individuals with certain conditions. These include:
  • Inflammatory skin tissue at the injection site
  • Significant facial asymmetry
  • Drooping eyelids (ptosis)
  • Excessive eyelid skin (dermatochalasis)
  • Deep skin scars
  • Thick oily skin
  • Glabellar lines that cannot be manually smoothed. 
You want to be careful when considering BOTOX® treatment for these individuals.

BOTOX® Administration Techniques 

Before you buy BOTOX® online, it's important to understand that the administration technique will vary depending on the condition you want to treat. Here are general guidelines for injecting BOTOX® for cosmetic purposes:
  • Use a 30-gauge needle and tuberculin syringe to inject affected facial muscles. Ensure correct injection volume and concentration
  • To reduce the risk of ptosis, avoid injecting near the levator palpebrae superioris, especially in individuals with larger brow-depressor complexes
  • Injection sites in the lateral corrugator muscle should be at least one cm above the bony supraorbital ridge and not less than one cm above the central eyebrow
  • Injections in the forehead area should be above the lowest fold produced when the individual elevates their forehead or at least two cm above the brow
  • In older individuals, avoid injecting the lower portion of the brow, as it is essential for raising the eyebrows to see
  • When injecting in the midpupillary line, inject one cm above the bony superior orbital margin, with a dose not exceeding five units
  • When treating lateral canthal wrinkles, inject at least 1.5–2 cm temporal to the lateral canthus and just temporal to the orbital rim
  • Inject superficially in a series of continuous blebs to avoid ecchymoses, with each injection at the advancing border of the previous one
  • A second treatment session may be needed for optimal results if several rows of deep forehead lines are present
  • Firmly massage sites laterally following injection
The entire procedure takes around ten minutes. 

BOTOX® Side Effects

Common side effects of BOTOX® include:
  • Pain, bruising, or swelling at the injection site
  • Headache
  • Muscle weakness or drooping
  • Flu-like symptoms
  • Dry eyes or excessive tearing
  • Difficulty swallowing or speaking
  • Allergic reactions
  • Spread of toxin beyond the injection site
Most of these side effects are mild and may subside after 24-48 hours. 

BOTOX® Vs. The Competition

The three main competitors of BOTOX® are DYSPORT, XEOMIN, and JEAVEU. Here’s what to know about them if you want to buy BOTOX® wholesale:

Similarities

  • All four brands contain botulinum toxin type A and are neurotoxin-based injectables used for both medical and cosmetical purposes
  • They are all FDA-approved
  • Their cosmetic purposes are similar, which include reducing wrinkles and treating muscle elasticity, spasms, and migraines 

Differences

  • The formulation for all four brands is different:
    • BOTOX® : onabotulinumtoxinA
    • DYSPORT: abobotulinumtoxinA
    • XEOMIN: incobotulinumtoxinA
    • JEUVEAU: prabotulinumtoxinA
  • XEOMIN is a naked neurotoxin, meaning it lacks the complex proteins found in BOTOX®  and DYSPORT, which results in a lower risk of allergic reactions
  • DYSPORT spreads and offers wider coverage, making it suitable for treating larger areas. In comparison, BOTOX®  and XEOMIN have localized effects, which are more helpful for precise treatments
  • DYSPORT has a shorter duration compared toBOTOX®, while XEOMIN lasts longer. JEUVEAU’s duration is similar to BOTOX®

Where Can I Buy BOTOX®?

If you’re looking to buy BOTOX® in bulk, reach out to one of our experts at Doctor Medica today. We’ll help you source the drug from reliable suppliers at the best possible price.

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