NEXPLANON®

What is NEXPLANON® Used For and How Does It Work?

NEXPLANON®, radiopaque etonogestrel implant 68mg, is not an intrauterine device (IUD) and it doesn’t contain estrogen. It is an implant that is placed in a patient’s arm. NEXPLANON® is a prescription birth control for the prevention of pregnancy. It may last up to 3 years. 

What does it mean when we say that it is over 99% effective? That means less than 1 pregnancy per 100 women who used NEXPLANON® for 1 year. 

How to Administer For Best Results?

It should be inserted subdermally to ensure palpability immediately post-insertion. Failure to do so may result in undetected implantation failure, leading to unintended pregnancies. 

Additionally, keep in mind that incorrectly removed implants may result in continued effects of etonogestrel, potentially leading to compromised fertility, ectopic pregnancy, or persistence or occurrence of adverse drug reactions.

NEXPLANON® is administered subdermally just under the skin at the inner side of the non-dominant upper arm. NEXPLANON must be removed no later than by the end of the third year. 

Read our comprehensive article on Nexplanon Side Effects.

Before You Buy: Essential Considerations

NEXPLANON should not be utilized in the following cases:

• Women with known or suspected pregnancy.
• Those with a current or past history of thrombosis or thromboembolic disorders.
• Individuals with liver tumors, benign or malignant, or active liver disease.
• Women experiencing undiagnosed abnormal genital bleeding.
• Those with known or suspected breast cancer, personal history of breast cancer, or other progestin-sensitive cancer, whether present or in the past.
• Individuals who have experienced allergic reactions to any component of NEXPLANON.

Drug Interactions

Speaking of drug interactions, drugs or herbal products that induce certain enzymes, such as CYP3A4, may lower the effectiveness of progestin hormonal contraceptives or increase breakthrough bleeding.

Bleeding Pattern Changes

NEXPLANON® implant can potentially influence a patient’s menstrual bleeding pattern, with 11.1% of women discontinuing treatment due to changes in their bleeding pattern, as documented in clinical trials of the non-radiopaque etonogestrel implant (IMPLANON®).

Insertion and Removal: Complications

Inserting and removing implants can cause issues, such as pain, altered sensation (paresthesia), bleeding, blood clots (hematomas), scars, or infection. Placing the implant in too deeply, such as in the muscle or a tissue layer, can potentially damage nerves or blood vessels. In some cases, implants have been found inside arm blood vessels or the pulmonary artery, often when inserted too deeply or inside a blood vessel. These situations can require special procedures, such as surgeries or endovascular techniques, to remove the implant.

If it is incorrectly inserted, too deeply placed, not palpable, encased in fibrous tissue, or has migrated, it might be difficult to remove. Prompt localization and removal are recommended if the implant cannot be palpated. Complete removal is essential to avoid continued effects of etonogestrel. Failure to remove the implant may lead to compromised fertility, ectopic pregnancy, or persistence or occurrence of adverse drug reactions.

Therefore, all healthcare providers performing insertion and removals of NEXPLANON® should receive training before they insert and/or remove the implant.

How and Where To Purchase Online

Patients may have the opportunity to obtain NEXPLANON® implants for free under the Affordable Care Act. Advise your patients to check with their insurance plan to determine the cost and coverage details. 

Healthcare facilities and providers may decide to shop for NEXPLANON® wholesale to ensure convenient access and availability for patients seeking this contraceptive option. By purchasing in bulk, healthcare providers can streamline inventory management and ensure consistent availability of contraceptive implants for their patients. 

Before you purchase NEXPLANON® online, it is necessary to ensure proper training and understanding of its insertion and removal procedures. Additionally, it’s important to order NEXPLANON® from verified and reputable sources to guarantee product authenticity and quality.