Manufacturer : Genzyme

Active Substance(s) : Hylan g-f 20

Strength : 8mg/ml

Pack Size : 1-6ml prefilled syringe

Accessories : Package insert, 2 traceability labels


$339.00 / unit

(you save $ 0)
Add 5 more units to your cart and save $60.00.
Quantity Our Price
1 - 5 pack(s) $339.00 USD
6 - 10 pack(s) $329.00 USD
11 - 20 pack(s) $324.00 USD
21+ pack(s) USD$319.00 319.00USD

What makes us the best place to buy Synvisc® One?

You can purchase online directly from our website or by phone. We are committed to offering you the best shopping experience and help you cut costs on your medical supplies and shipping fees. The process is simple. Just add your favourite product to your cart, submit your mailing information and we will confirm your order in no time. You can also call in and one of our experienced customer service representatives can capture your order right away. You can benefit from our lowest prices by ordering in bulk. Check out our wholesale price discounts. Help your patients feel better as they cope with their osteoarthritis while resting assured you receive ONLY authentic Synvisc products.

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Product Information

What is it?

This product is an injection for relief of osteoarthritis symptoms such as inflammation and pain. This medical device is an injectable made of sodium hyaluronate, and it is also called Hylan G-F 20. Sodium hyaluronate is found throughout the body including in the knee joint and other joints, and the sodium hyaluronate in it comes from chicken combs.

Why do patients choose this product?

Osteoarthritis can be a debilitating disease, but this product can help reduce pain and inflammation. This orthopedic injectable can supplement or replace other osteoarthritis treatments that have stopped working, such as pain medication, physiotherapy, and exercise, and it can help patients delay knee surgery.

How is it different from regular Synvisc®?

Its advantage over other osteoarthritis injections such as SYNVISC® is that it requires only one injection instead of three or more to provide full osteoarthritis relief. This can be helpful for patients that find returning each week for multiple injections to be inconvenient.

How does it help with Osteoarthritis?

Osteoarthritis is the degradation of cartilage in the joint, often happening with age, repetitive stress, injury, or obesity. Osteoarthritis is also associated with the degradation of synovial fluid, which is the fluid that is normally present in the knee joint to provide lubrication and a cushion. With little protection in the knee joint, there is friction as the bones move, causing inflammation and pain. When you inject it directly into your patient's knee joint, the sodium hyaluronate fluid provides a similar function as the synovial fluid, lubricating and cushioning the joint as your patient moves. This reduces friction, leading to a reduction in pain and inflammation.

What are the most common side effects?

These include pain at the injection site, knee pain, a feeling of warmth, and swelling of the knee. More rare side effects include skin rash and itching, infected knee joint, flushed face and swollen lips, headache, dizziness, muscle pain, calf cramps, nausea, pain on one side of the body with nausea, tiredness, and anxiety, and a rapid heartbeat. This injectable could cause an allergic reaction with shortness of breath, difficulty breathing, and hives, and since the ingredients of this product come from chicken combs, if your patients have a bird, egg, or feather allergy, they should not get it injections. Other contraindications include a knee infection, skin infection in the injection area, blood clots, and circulation problems especially in the legs. The effect of this injectable on women who are pregnant or breastfeeding is not known.

When will it start to work?

This injectable is designed to deliver relief from osteoarthritis pain with one single injection. In a clinical trial, many patients experienced maximum relief from their osteoarthritis symptoms about a month after receiving an injection.

How long does it last?

After application, most people continue to experience osteoarthritis relief for about six months, and at that time, you can give your patient another injection if they wish.



Through, cosmetic and orthopaedic medications are offered wholesale to licensed practitioners, clinics and hospitals. Go to, call 1-866-343-2413, or e-mail for more information.


*Doctor Medica offers only genuine products manufactured by Genzyme. All brands listed here including it are the trademarks of their respective owners and Doctor Medica is not affiliated with them in any way.

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