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Three Most Popular Facial Fillers Against Wrinkles In 2023

Dermal Fillers

Written by Doctor Medica’s Editorial team

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Smooth and radiant skin symbolizes youth and good health, making you look attractive. The internal skin structure starts to degrade with age or due to some diseases or extreme diets. The underskin fat layer becomes thinner, negatively impacting the skin because a fat layer makes the skin moisturized and elastic. As a result, wrinkles and deep folds appear on the face.

Dermal fillers for the face are a group of products that can fill the skin with moisture, plump it, and support it for some time. After dermal filler injections, the existing wrinkles become smoother, and new wrinkles do not appear. There are several types of fillers for the face based on the main active compound. All of them can be effective treatments in cosmetology and plastic surgery.

Doctor Medica offers the option to purchase dermal fillers online, including the best brands, Juvéderm and Restylane. Juvéderm and Restylane offer a collection of fillers that can be used for lips, cheekbones, temple hollows, and other critical zones. 

Types of Facial Wrinkles Treated by Facial Fillers

The injections for wrinkles can fix the shape and look of many body parts: face, neck, hands, and others. By origin, there are five types of wrinkles:

  • Expression lines – appear on the most active facial parts, like the forehead.
  • Gravity folds – appear as the result of ptosis, skin sagging with age.
  • Atrophic wrinkles – the result of aging and skin fat degradation.
  • Compression wrinkles – a result of constant repetitive compression in one zone, for example, sleeping on a high pillow.  
  • Elastic wrinkles – skin loses elasticity because of external factors, like sun rays or smoking.

Here are several types of facial wrinkles to treat with facial dermal fillers.

  • Forehead Lines: Sometimes called wisdom wrinkles, these are the horizontal lines running across the top of the T-zone (forehead).

  • Worry Lines: When people worry, they knit their brows. This gesture creates an “eleven” between the brows.
  • Crow’s Feet: The radiating wrinkles from the outer eye corner remind the bird’s footprint, so that is called crow’s feet.
  • Bunnies: These are horizontal wrinkles on the nose between the eyes.
  • Nasolabial Folds: Vertical folds that run from the nose to the lips and are also known as laugh lines.
  • Lip Lines: These lines are numerous, thin, and short lines around the mouth’s perimeter.

Hyaluronic acid is the most well-known substance for fillers for facial wrinkles, but this segment is not limited to HA. Aesthetic providers comparing Restylane vs Botox or Juvederm vs Botox should look into the advantages and risks of these formulations to determine which best suits the patient’s concerns.

Botulinum Toxin

Botulinum toxin is a natural neurotoxin widely used in cosmetology. The microdose of toxin under the dermis blocks the nerves and paralyzes the tiny facial muscles. When the muscles stop moving, the skin at the injection site becomes smoother. The effect of Botox is limited: with time, the body neutralizes the toxin and renews the muscle movements. Botulinum toxin injections can be combined with other fillers for better effects.

Collagen Fillers

Collagen is a natural protein that the body produces. In the skin, collagen works as a support and an elastic base. Young skin contains a lot of collagen, and when the skin moves, it returns to the same position due to collagen. With age, natural collagen production decreases. Due to facial muscle movements, wrinkles and folds appear. Collagen injections restore skin elasticity and help it to get smoother.

Sculptra is a well-known facial dermal filler that stimulates natural collagen production. Some sources mention Sculptra as the dermal filler for injections with the longest-lasting effect on the market, while the Sculptra effect can last up to two years. This dermal filler is recommended for patients with HIV/AIDS and lipoatrophy.

Abdominal Fat

Among the natural substances for beauty injections, abdominal fat takes the top place in terms of popularity. The principle is elementary: the injector collects the fat from the abdomen and injects it into a specific facial zone. It is the safest procedure from the allergic reaction point of view: the body does not reject its own fat. This procedure helps restore volume in some facial and body areas.

Hyaluronic Acid Fillers

Hyaluronic acid is a cornerstone of the beauty injections business. This compound is naturally produced in body tissues and binds water under the skin. Due to HA, skin looks moist and elastic. Approximately 40 years ago, scientists discovered synthetic HA production. Since that time, HA products have been widely used in cosmetology and medicine. Hyaluronic acid is a gel that replaces lost natural moisture. Whether for wrinkles or to achieve the benefits of lip fillers, HA dermal filler injections can deliver natural-looking and safe outcomes.

Restylane, a product of the Swiss-based Galderma company, also offers several types of dermal fillers of different strengths for the face, neck, and even hands.

Calcium Hydroxylapatite Fillers

Calcium Hydroxylapatite (CaHA) is a compound found naturally in human bones, making it biocompatible and biodegradable. Injectable facial fillers with this active ingredient contain CaHA microspheres in an aqueous carboxymethylcellulose gel carrier. CaHA fillers help restore volume in target facial areas and smooth wrinkles. The effect of CaHA type dermal fillers lasts approximately 12 months. Then the biodegradable capsules dissolve in body tissues.

Radiesse is the most popular brand of CaHA dermal fillers. It is produced by German Merz Pharma and smooths small wrinkles and deeper facial folds. The product is available with and without lidocaine. Radiesse products vary by strength, e.g., by the quantity of active compound in 1 milliliter of a gel. Products with higher strength should be used for deeper folds, while gels with lower strength are intended for active facial areas like eye corners.

Poly-L-lactic Acid Fillers

Poly-L-lactic acid is a polyester produced from plant sugars, such as fermented sugarcane, corn, maize, and others. During fermentation, sugar transforms into lactic acid and then into polylactic acid. This compound is less popular than HA or CaHA but is also effective. Poly-L-lactic acid is the primary material for dissolvable body implants that help renew natural collagen production in the target body parts. Also used for bone engineering, Poly-L-lactic acid is also an effective type of dermal filler.

Ellanse is a dermal filler with poly-L-lactic acid beads in the supporting gel. The filler is produced in the Netherlands by Aqtis Medical. This universal dermal filler works best for deep acne scars and facial folds, and the polymer beads add fullness in these areas and restore volume.

How Facial Fillers Work

Despite the different compounds in popular types of facial dermal fillers, they work in the same way.

The Injection Processes

Before the injection, a patient should ensure the skin on the injection site is ready for a procedure. It should be healthy, with no dermal issues, and carefully cleaned. The injector cleans the skin and marks the injection points, for example, along the deep fold. In most cases, an injector uses lidocaine to minimize the pain.

Then the injection process starts. An injector injects small doses of a filler into the middle-deep layers of the patient’s skin.

There are several injection techniques. A tunnel technique uses a syringe or cannula to inject a filler under a deep wrinkle or a fold. A point technique is a series of microinjections close to one another. The stretching technique involves putting the skin under tension to isolate the injection site. A dual plane is the filler injection into different skin layers in one zone, such as the middle and deep skin layers.

Each injection technique should be used at the proper injection site and combined with the best-fit dermal fillers. So, only a trained injector can conduct the procedure.

The session continues for 40-60 minutes. Some dermal fillers require more than one session, like 2 or 3. The full effect of a filler can be visible in 7-10 days. The duration of the effect depends on the dermal filler type, product characteristics, individual metabolism, the patient’s lifestyle, and other factors.

Risks and Side Effects

Most dermal fillers for the face provoke minor side effects after the procedure. They include irritation at the injection site, itching, redness, bruising, etc. Sometimes a patient feels a headache, high body temperature, and other flu-like symptoms. Typically, they are gone in 48 hours; if they last longer, a patient should contact the healthcare provider.

A patient can rarely suffer from an allergic reaction or significant consequences like infection, inflammation, severe pain, etc. These cases require immediate contact with the therapist.

How to Reduce the Risk of Complications

Three main safety rules help reduce the risk of complications.

First, a patient should check with the therapist before the procedure. The therapist should rule out any skin and general health issues at the injection site. Some diseases and conditions can be a reason to postpone or reject the procedure.

Second, only authentic fillers for facial lines can be used for injections. To avoid fake products, buy dermal fillers online on global and verified facial filler suppliers. A broad range of authentic dermal fillers for facial wrinkles from the best global brands at affordable prices is available for online purchase.

Third, all injections should be conducted by a certified healthcare specialist. One of the most dangerous consequences is minor blood vessel damage, and in the worst case, it can result in body tissue necrosis. That is why a specially trained injector can perform the procedure to find the best injection site.

Conclusion

Dermal filler facial injections are a popular procedure in cosmetology. The procedure helps restore volume in some facial areas, plumps the skin to make it smoother, and reduces wrinkles. In this way, a face looks younger and more attractive. The procedure is almost 100% safe and cost-effective; its effects become visible within several days and last for months. Naturally, the demand for dermal filler injections is skyrocketing.

There are several dermal filler types: hyaluronic acid fillers, calcium fillers, and collagen fillers. When injected in middle-deep skin layers, they restore volume and stimulate natural collagen production. The primary rule for effective dermal filler injection is to follow safety rules: do not start a procedure without the therapist’s approval, and use only authentic products and a trained injector.

FAQs

1. What is the best wrinkle filler for deep wrinkles?

Hyaluronic acid dermal fillers are the best for deep wrinkles. Other dermal fillers can also be used for deep wrinkles and facial folds, but the natural components that bind moisture and plump skin are the safest option. HA fillers have various viscosities combined with a long-lasting effect.

2. What is the longest-lasting filler for wrinkles?

The dermal filler effect time depends on density, and a higher share of active compounds prolongs the effect while decreasing filler density. Dermal fillers with high density can block the movement of the facial muscles, so they are recommended for the less active zones. The longest possible effect, for now, is up to 2 years; hyaluronic fillers Juvederm and Restylane offer this effect.

There are several popular filler types – Calcium fillers, polylactic acid fillers, collagen fillers, and so on. All of them can be effective for facial wrinkles. However, hyaluronic acid fillers are the most popular as they have the most extensive history of use. Juvéderm and Restylane product lines are in great demand among HA fillers.

4. What is the best filler for older skin?

Three filler brands are the most effective for mature or sagging skin: Restylane, Juvéderm, and Radiesse are fillers with cross-linked hyaluronic acid. They can hold 1,000 times their weight in water and restore lost volume in the mature face, plumping up the skin.

About: Doctor Medica is your trusted supplier of top-quality dermal fillers, viscosupplements, and more for your medical practice. We offer genuine products from leading brands at the lowest prices.

Citations

[1] Cockerham, Kimberly, and Victoria Hsu. “Collagen-Based Dermal Fillers: Past, Present, Future.” Facial Plastic Surgery, vol. 25, no. 02, May 2009, pp. 106–13. https://doi.org/10.1055/s-0029-1220650.

[2] Pavicic, Tatjana. “Calcium Hydroxylapatite Filler: An Overview of Safety and Tolerability.” PubMed, 1 Sept. 2013, pubmed.ncbi.nlm.nih.gov/24002146.

[3] Sickles, Christine K., et al. “Poly-L-Lactic Acid.” StatPearls – NCBI Bookshelf, 28 Feb. 2024, www.ncbi.nlm.nih.gov/books/NBK507871/?report=reader.


The content on this page has been written and fact-checked in accordance with our Editorial Policy. Clinical claims are sourced from peer-reviewed literature, regulatory documentation, and manufacturer specifications. Where citations are provided, it is always in accordance to our editorial standards.