Juvederm Volite: Potential Side Effects And Precautions

A box of Juvedern Volite

Juvederm Volite is a revolutionary product from one of the world's leading cosmetic injectable brands. Not a traditional dermal filler, it is designed to intensely hydrate the skin and treat fine lines, improving skin quality for up to 9 months.

Juvederm Volite has been proved to be safe and is also FDA-cleared. However, there might still be side effects a medical practitioner should know of and inform patients before providing any treatments.

Common Side Effects of Juvederm Volite

Common side effects of Juvederm Volite include but are not limited to:

  1. Inflammatory reactions at the injection site, including redness, edema, and erythema;
  2. Itching and/or tingling;
  3. Pain at the injection site;
  4. Bruising;
  5. Hypersensitivity;
  6. Induration (hardening) or nodules (lumps) at the injection site;
  7. Staining or discoloration at the injection site;
  8. Poor or weak filling effect.

Rare Adverse Effects of Juvederm Volite

There have been reports of serious yet extremely rare side effects of Juvederm Volite:

  1. Abscesses;
  2. Granuloma;
  3. Temporary or permanent vision impairment;
  4. Cerebral ischemia (insufficient blood flow to the brain) or cerebral hemorrhage leading to stroke.

You should stop injection immediately if a patient has symptoms, including vision changes, signs of stroke, skin blanching, or unusual pain during or soon after the injection. Ensure the patient receives prompt medical attention and possibly sees a specialist.

Recommended Precautions When Injecting Juvederm Volite Dermal Fillers

The injection of Juvederm Volite and other dermal fillers is only allowed for certified medical practitioners. To ensure the safety of the process, please follow the precautions listed by the manufacturer:

  • The product can only be used for intradermal injection. Intravascular injections can lead to embolization (blocked blood vessels), vessel occlusion (blockage), ischemia (inadequate blood supply), or infarction (obstruction of blood supply causing local tissue death).
  • Not for use in breast augmentation or reconstruction;
  • Not for use in patients who have untreated epilepsy; patients who tend to develop hypertrophic scarring; patients with a known hyaluronic acid sensitivity or gram-positive bacterial protein sensitivity or lidocaine sensitivity; or patients with porphyria.
  • Not for use in pregnant or breastfeeding patients and children;
  • Not for use in areas with skin inflammation or infection, such as acne and herpes.
  • Not for simultaneous use with laser treatment, deep chemical peels, or dermabrasion. Do not inject this product if there is a significant inflammatory reaction from surface peels.
  • Not for injection into a site with a permanent implant.
  • There is no clinical data about injecting into an area already treated with a filler or product from another brand.
  • There is no data regarding the efficiency and tolerance of this product in patients who currently have, or have a history of, autoimmune deficiency or who are undergoing immunosuppressive therapy. Decide case-by-case whether to inject, depending on the nature of the disease and its treatment. Monitor these patients and perform a preliminary skin test for hypersensitivity before treatment, avoiding injection if the disease is active.
  • There is no data regarding tolerance in patients with a history of severe or multiple allergies. Decide case-by-case whether to inject, depending on the nature of the allergy. Especially monitor these patients. Propose a skin test for hypersensitivity or administer a suitable preventative treatment before injection. The manufacturer does not recommend injecting if there is a history of anaphylactic shock.
  • Perform a skin test for hypersensitivity before injecting patients who have a history of streptococcal disease, including recurrent sore throats or acute rheumatic fever. The manufacturer does not recommend injecting if there is acute rheumatic fever with heart complications.
  • Warn patients of potential increased risk of bleeding and hematomas (bruising) during injection if they are taking anti-coagulation drugs; using substances that can prolong bleeding, such as warfarin, acetylsalicylic acid, and nonsteroidal anti-inflammatory drugs; or using substances that increase coagulation time, such as herbal supplements containing garlic or ginkgo biloba.
  • Since there is lidocaine in this product, the manufacturer does not recommend combining it with certain drugs that reduce or inhibit hepatic metabolism, such as cimetidine and beta-blockers.
  • Since there is lidocaine in this product, use caution in patients with symptoms of cardiac conduction disorders.
  • Inform the patient that they should not use makeup for at least twelve hours following injection.
  • Inform the patient that they should avoid extended exposure to the sun, UV, and temperatures below freezing, and sauna or hammam sessions, for at least two weeks following treatment.
  • This product is compatible with magnetic resonance imaging (MRI) fields.
  • The hyaluronic acid in this product is incompatible with benzalkonium chloride and other quaternary ammonium salts. Do not allow it to come into contact with these substances or with medical/surgical instruments treated with these substances.
  • There is no known interaction with other local anesthetics.
  • Do not modify this product, or it could affect sterility, homogeneity, and product performance.
  • Check the expiry date on the product label before use.
  • If syringe contents are cloudy or show signs of separation, do not use it.
  • Do not reuse or re-sterilize. Sterility cannot be guaranteed.
  • Do not try to straighten a bent needle. Instead, replace it.

Note on articles: These articles are not endorsed by DoctorMedica nor reviewed for medical accuracy. Similarly, views and opinions expressed are those of the author only. Articles are meant for informational purposes only. Ask your doctor for professional medical advice.