Juvederm Volite Side Effects

A box of Juvedern Volite

Most Common Side Effects

  • Inflammatory reactions, such as redness, edema, and erythema, possibly with itching, pain, pressure, or paresthesia (tingling). These may occur after the injections and last for a week.
  • Hematomas (bruising).
  • Induration (hardening) or nodules (lumps) at the injection site.
  • Staining or discoloring at injection site, especially with too superficial an injection, called the Tyndall effect.
  • Poor or weak filling effect.
  • Rare but serious side effects after intravascular injection and tissue compression. These may include temporary or permanent vision impairment, blindness, cerebral ischemia (insufficient blood flow to the brain) or cerebral hemorrhage leading to stroke, skin necrosis (death), and damage to underlying structures. Stop injection immediately if patient has symptoms including vision changes, signs of stroke, skin blanching, or unusual pain during or soon after the injection. Ensure patient receives prompt medical attention and possibly sees a specialist if there is an intravascular injection.
  • Rarely, abscesses, granuloma, and immediate or delayed hypersenstivity.


  • Intended for injection by qualified medical practitioners with appropriate training and experience in injection techniques and anatomy knowledge at injection site.
  • Only for intra-dermal injection.
  • Not for use in breast augmentation or reconstruction.
  • Take into account the presence of Lidocaine in this filler.
  • Do not inject in the eyelids.
  • Not for intravascular injection (into blood vessels) because this could cause embolization (blocked blood vessels), vessel occlusion (blockage), ischemia (inadequate blood supply), or infarction (obstruction of blood supply causing local tissue death).
  • Do not overcorrect.
  • Not for use in patients who have untreated epilepsy; patients who tend to develop hypertrophic scarring; patients with a known hyaluronic acid sensitivity or gram-positive bacterial protein sensitivity since this hyaluronic acid is produced using Streptococcus-type bacteria; patients with a known Lidocaine sensitivity or amide-type local anesthetic sensitivity; or patients with porphyria.
  • Not for use in pregnant patients.
  • Not for use in breastfeeding patients.
  • Not for use in children.
  • Not for use in areas with skin inflammation or infection, such as acne and herpes.
  • Not for simultaneous use with laser treatment, deep chemical peels, or dermabrasion. Do not inject this filler if there is a significant inflammatory reaction from surface peels.
  • There is no clinical data about injecting into an area already treated with a filler from another brand.
  • The manufacturer recommends not injecting into a site with a permanent implant.
  • Injections carry an infection risk. Use standard precautions relating to injectable materials.
  • There is no data regarding efficiency and tolerance of this dermal filler in patients who currently have, or have a history of, autoimmune deficiency or who are taking immunosuppressive therapy. Decide case-by-case whether to inject, depending on the nature of disease and its treatment. Specifically monitor these patients, and perform a preliminary skin test for hypersensitivity before treatment, avoiding injection if the disease is active.
  • There is no data regarding tolerance in patients with a history of severe or multiple allergies. Decide case-by-case whether to inject, depending on the nature of the allergy. Specifically monitor these patients. Propose a skin test for hypersensitivity or administer suitable preventative treatment before injection. The manufacturer does not recommend injecting if there is a history of anaphylactic shock.
  • Perform a skin test for hypersensitivity before injecting patients who have a history of streptococcal disease, including recurrent sore throats or acute rheumatic fever. The manufacturer does not recommend injecting if there is acute rheumatic fever with heart complications.
  • Warn patients of potential increased risk of bleeding and hematomas (bruising) during injection if they are taking anti-coagulation drugs; using substances that can prolong bleeding, such as warfarin, acetylsalicylic acid, and nonsteroidal anti-inflammatory drugs; or using substances that increase coagulation time, such as herbal supplements containing garlic or ginkgo biloba.
  • There is no safety data on injecting more than 20 ml of dermal fillers per 60 kg (130 lbs) body mass per year.
  • Since there is Lidocaine in this filler, the manufacturer does not recommend combining with certain drugs that reduce or inhibit hepatic metabolism, such as cimetidine and beta-blockers.
  • Since there is Lidocaine in this filler, use caution in patients with symptoms of cardiac conduction disorders.
  • Inform patient they should not use makeup for at least twelve hours following injection.
  • Inform patient they should avoid extended exposure to sun, UV, and temperatures below freezing, and sauna or hammam sessions, for at least two weeks following treatment.
  • This product is compatible with magnetic resonance imaging (MRI) fields.
  • The hyaluronic acid in this filler is incompatible with benzalkonium chloride and other quaternary ammonium salts. Do not allow the filler to contact these substances or medical-surgical instruments treated with these substances.
  • There is no known interaction with other local anesthetics.
  • Do not modify this product or it could affect sterility, homogeneity, and product performance.
  • Check expiry date on product label before use.
  • If syringe contents are cloudy or show signs of separation, do not use.
  • Do not re-use. Sterility cannot be guaranteed.
  • Do not re-sterilize.
  • Do not try to straighten a bent needle. Throw away and replace.

Note on articles: These articles are not endorsed by DoctorMedica nor reviewed for medical accuracy. Similarly, views and opinions expressed are those of the author only. Articles are meant for informational purposes only. Ask your doctor for professional medical advice.

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