Non-Surgical Lip Augmentation

Dermal Fillers


Last Updated On: 2024-01-12

Lip enhancement has become increasingly popular, and non-invasive lip fillers appeared as a highly sought-after solution.

Doctor Medica team

Lip fillers are cosmetic injectables used to augment and enhance lip shape, volume, and definition. They are designed to provide natural-looking results and address various aesthetic concerns such as thin lips, asymmetry, or loss of volume due to aging or other factors.

Non-invasive lip fillers offer a minimally invasive alternative to surgical procedures, allowing patients to achieve their desired lip enhancement without significant downtime.

What Is a Non-Invasive Lip Filler?

The concept of “needleless fillers” refers to the technique and device used (such as the hyaluron pen) rather than specific branded products. Needleless fillers, such as those performed with a hyaluron pen, are an alternative technique for delivering hyaluronic acid or other fillers into the skin without using traditional needles. 

The hyaluron pen is a special device that uses pressure to force the filler substance through the skin via a narrow opening, creating a fine stream of the product. It is a popular device used for needleless lip filler administration, but to achieve safe and effective results, the technique and skill of the practitioner are critical factors.

Hyaluron pens are compatible with various hyaluronic acid-based fillers, and the choice of filler may depend on the preferences and expertise of the practitioner. Some commonly used hyaluronic lip fillers with no needles for needleless techniques include:

The availability and specific brands of fillers used with needleless techniques may vary depending on the region and the doctor’s preferences.

Hyaluronic Acid Lip Infusion

One popular type of needle-free lip filler technique is hyaluronic acid lip infusion. It provides a non-invasive solution for lip enhancement by infusing a gel-like substance into the lips, instantly adding volume and improving their shape. The HA lip infusion technique caters to those who may feel hesitant or anxious about needle-related procedures while still providing the benefits of hyaluronic acid treatment with a product like Juvederm Volite.

This process involves the infusion of hyaluronic acid serum into the skin using a pressurized device (hyaluron pen), which allows the serum to penetrate the top layers of the skin. HA, lip infusion is suitable for individuals seeking to improve collagen production and address specific fine lines or scar tissues within the lips, all while avoiding traditional needle-based treatments. The results of lip infusion are natural-looking and can be tailored to each patient’s preferences.

Unlike traditional needles, which do have a slight risk of popped blood vessels and bruising due to the injection occurring in the middle dermis layers, the hyaluron pen targets the epidermis, creating hyaluronic acid absorption via nano-scale molecules injected into the upper layers of the skin.

Here are some key points about using needleless fillers with the hyaluron pen:

Operating Mechanism: The hyaluron pen works by utilizing a spring-loaded mechanism or a pressurized air system to propel the filler material through the pen’s nozzle into the targeted area of the skin.

Administration: The pen is pressed against the skin at a specific angle, and the filler substance is released in a controlled manner, forming tiny deposits under the skin. The pressure that the pen creates allows the filler to penetrate the skin without using traditional needles.

Benefits: Needleless fillers with the hyaluron pen are often promoted as a potentially less invasive and more comfortable option than traditional injections. It is arguably a less painful solution, as the pressure sensation is typically milder than that of a needle injection.

Considerations: The technique and efficacy of needleless fillers, including those performed with the hyaluron pen, are still subjects of discussion and ongoing research. The effectiveness, safety, and longevity of results may vary among individuals, and further scientific evidence is needed to support the claims and assess potential risks and complications.

While needleless fillers infused to the lips with the hyaluron pen may be marketed as a non-invasive or less invasive option, they still involve introducing external substances into the skin.

What are the Differences Between Hyaluron Needleless Injections and Regular Filler Injections?

Understanding the differences between these two types of injections is essential for doctors looking to provide comprehensive guidance and tailored treatment options to their patients. Therefore, let’s explore the dissimilarities between these two methods.

One of the primary advantages of hyaluron needleless injection is its potential to offer a more comfortable experience for patients. For individuals with needle phobia or anxiety, this technique can be an appealing alternative that reduces the discomfort and stress associated with traditional injections. The absence of needles also minimizes the risk of needle-related complications, such as bruising or bleeding at the injection site.

Another notable advantage of using lip fillers without needles is the precise and controlled delivery of the filler. The high-pressure flow allows for even distribution of the filler substance, resulting in more uniform and natural-looking results. This technique can be particularly advantageous when it comes to achieving symmetrical lip enhancement or addressing specific areas of concern with precision.

On the other hand, regular filler injection involves using fine-gauge needles to inject the filler substance directly into the lips. This traditional method has been widely used for lip augmentation and has a long-established track record in cosmetic procedures. The needles used in regular filler injections come in different sizes, allowing for various techniques and levels of precision.

Another significant difference between regular filler and needleless injections is the delivery depth. Regular filler injection can deposit the filler substance into different skin layers, such as the dermis or subcutaneous tissue, depending on the desired results. The injection depth can be adjusted based on the patient’s needs and the targeted areas of enhancement.

Regular filler injection also offers versatility in terms of the types of fillers that can be used. Different formulations of hyaluronic acid or other compatible substances may be selected based on the patient’s goals, skin condition, and medical history. This flexibility allows doctors to customize treatments to suit each individual’s unique requirements and preferences.

In terms of longevity, both needleless lip fillers and regular filler injections offer temporary results. The duration of the lip filler effects depends on various factors, including the specific product used, individual metabolism, and lifestyle factors. Typically, lip fillers last several months before natural absorption occurs, but non-invasive lip fillers dissolve quicker, necessitating follow-up treatments to maintain the desired lip appearance.

Advantages of Non-Surgical Lip Fillers

Non-surgical lip fillers offer several advantages for patients and doctors:

  • They provide immediate results, allowing patients to see the transformation in their lips right after the treatment.
  • The treatment procedure is relatively quick and can be administrated

 in a doctor’s office setting without the need for general anesthesia.

  • Non-invasive lip fillers also offer a reversible option, as the effects are temporary and can be adjusted or dissolved if desired.
  • The procedure requires minimal downtime, so patients can resume their normal daily activities shortly after the treatment.

Disadvantages of Non-Surgical Lip Fillers

While non-surgical lip fillers have many benefits, it’s essential to also consider the potential drawbacks. One key aspect is the temporary nature of the results. Most non-invasive lip fillers only last for up to a year or shorter, and repeated treatments are typically required to maintain the desired lip appearance.

Additionally, there may still be temporary side effects such as swelling, bruising, or minor discomfort at the injection site. Doctors should discuss these potential risks with patients before the treatment and ensure they have realistic expectations before starting the procedure.


Needleless lip injections, such as hyaluronic acid lip infusion, offer a non-surgical approach to lip enhancement. They provide immediate and natural-looking results, with minimal downtime and the option for reversibility.

However, doctors must carefully assess patients, discuss expectations, and consider the short-lived nature of the results. By understanding the advantages and disadvantages of non-surgical lip fillers, doctors can guide their patients in making informed decisions and achieving satisfying outcomes.


How long do non-invasive lip fillers last?

The longevity of needleless lip fillers can vary depending on several factors, including the specific product used, individual metabolism, lifestyle choices, and the technique employed during the procedure. In general, non-invasive lip fillers offer temporary results lasting several months before the body naturally absorbs the filler substance.

On average, non-invasive lip fillers can last anywhere from six months to a year. However, some individuals may experience longer-lasting results, while others may notice that the effects wear off more quickly.

Maintaining the desired lip appearance often requires follow-up treatments. Therefore, regular touch-up sessions are typically needed to sustain the desired level of lip volume and shape.

Non-invasive hyaluronic lip fillers also offer a reversible solution and can be dissolved using an enzyme called hyaluronidase. This provides a level of flexibility and control in achieving the desired lip aesthetics.

Are non-invasive lip fillers safe?

Non-invasive lip fillers, particularly those made with hyaluronic acid (HA) as the main ingredient, are considered safe; however, some potential risks and considerations need to be taken into account. These may include:

  • Temporary swelling and bruising after lip filler treatment. This typically resolves within a few days to a week.
  • Some individuals may experience mild redness, tenderness, or itching at the treatment site. These reactions are usually temporary and subside on their own.
  • Achieving perfectly symmetrical lips can be challenging, and there is a slight risk of uneven results or asymmetry. Skilled practitioners aim to achieve balance and natural-looking results, but there may be subtle differences between the two lips.
  • While rare, there is a small risk of infection at the injection site. Therefore, it is crucial to have the procedure performed by a qualified professional to minimize this risk.


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Chirico F, Colella G, Cortese A, Bove P, Fragola R, Rugge L, Audino G, Sgaramella N, Tartaro G. Non-Surgical Touch-Up with Hyaluronic Acid Fillers Following Facial Reconstructive Surgery. Applied Sciences. 2021; 11(16):7507.

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Baspeyras M, Roux E, Lavieille JP, et al. An innovative hyaluronic acid gel for lip enhancement: a prospective, multicenter, controlled, randomized, clinical trial. J Cosmet Dermatol. 2012;11(3):202-209. doi:10.1111/j.1473-2165.2012.00623.x

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Sundaram H, Cassuto D. Biophysical Characteristics of Hyaluronic Acid Soft-Tissue Fillers and Their Relevance to Aesthetic Applications. Plast Reconstr Surg. 2013;132(4 Suppl 2):5S-21S. doi:10.1097/PRS.0b013e31829a9ad1.

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