Lanluma vs. Sculptra – Comparing Body Sculpting Treatments

The global body contouring market is experiencing robust growth, valued at approximately USD 8.9 billion in 2024 and expected to rise to USD 14.6 billion by 2033, driven by a steady compound annual growth rate (CAGR) of 5.42%. This expansion reflects a growing preference for non-invasive aesthetic procedures that deliver effective results with minimal downtime.

Two prominent treatments in this space are Lanluma and Sculptra, both poly-L-lactic acid (PLLA) injectables known for their collagen-stimulating properties and volume-restoring effects. While Sculptra has traditionally been favored for facial rejuvenation, Lanluma offers versatility for both facial and body contouring, targeting areas such as the buttocks, hips, and thighs.

This article provides a comprehensive comparison of Lanluma and Sculptra, exploring their mechanisms of action, treatment areas, longevity of results, and suitability for various aesthetic goals. The objective is to guide readers in selecting the most appropriate body sculpting option tailored to their individual needs.

Key Takeaways

• Lanluma and Sculptra are poly-L-lactic acid (PLLA) injectables that stimulate collagen production to restore volume and gradually improve skin firmness.
• Lanluma offers two formulations—Lanluma V for facial areas and Lanluma X for larger body areas such as the buttocks, hips, and thighs—providing versatility for body contouring.
• Sculptra is FDA-approved for facial volume loss but is increasingly used off-label for body areas like hips and thighs, though scientific evidence for these uses is limited.
• Currently, no formal scientific studies confirm the effectiveness and patient satisfaction of either product specifically for hip dips, thighs, or arms. Still, many aesthetic clinics offer these treatments based on experience.
• Both treatments require multiple sessions spaced weeks apart to achieve gradual, natural-looking results, with effects lasting up to 18–24 months or longer.

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Composition and Mechanism of Action

Both Lanluma and Sculptra are composed of poly-L-lactic acid (PLLA), a synthetic, biodegradable compound that stimulates the body’s collagen production. Once injected, PLLA particles encourage tissue regeneration, helping restore lost volume and gradually improving skin firmness.

Key Differences

• Lanluma is available in two specialized formulations: Lanluma V, designed for delicate facial areas to restore volume and smooth fine lines, and Lanluma X, formulated for larger body areas such as the buttocks, thighs, and hips. Both offer a non-surgical approach to body contouring.
• Sculptra was initially FDA-approved for treating facial lipoatrophy but has become popular for facial rejuvenation, including cheeks, temples, and jawline. Though not FDA-approved for body areas like hips or thighs, it is increasingly used off-label for these purposes.

While both treatments are generally well-tolerated, it is important to discuss Sculptra or Lanluma side effects with a qualified provider. Similar to other collagen-stimulating injectables, these can include temporary swelling, redness, or bruising at the injection site. Practitioners should always inform their patients about potential risks, especially when considering off-label body applications.

It’s also important to note that no published scientific studies support the effectiveness or patient satisfaction of Lanluma or Sculptra for treating hip dips, thighs, or arms. Likewise, scientific literature detailing the distinct formulations of Lanluma V and Lanluma X is lacking. 

However, many aesthetic clinics offer these treatments based on practitioner experience and patient demand. Patients should approach these options with informed caution and seek providers who prioritize safety and transparency.

Treatment Indications and Areas

When deciding between Lanluma vs Sculptra, it helps to look at which areas each treatment best suits. Both collagen-stimulating fillers cater to different needs depending on the target area and desired results.

Sculptra – Common Uses	Lanluma – Ideal Uses
Facial volume loss (cheeks, temples)	Buttocks (non-surgical BBL)
Smile lines and marionette lines	Hip dips
Jawline and chin definition	Thighs and arms
Off-label use for buttock augmentation	Facial contouring (Lanluma V)

Sculptra is popular because of its ability to deliver subtle, natural facial rejuvenation. Lanluma’s dual formulations allow it to address larger body areas, providing a non-invasive alternative to implants or fat grafting for body sculpting.

Efficacy, Longevity, and Patient Satisfaction

Lanluma and Sculptra promote gradual, natural-looking enhancements by stimulating the body’s collagen production over time. Unlike hyaluronic acid fillers that provide immediate volume, these biostimulators work beneath the surface, resulting in subtle yet long-lasting improvements that evolve with your skin.

Treatment Timeline

• Lanluma: Initial results emerge around 6 to 8 weeks post-treatment, as collagen production ramps up. Patients typically observe continued contouring and firmness improvements over the next 3 to 6 months.
• Sculptra: Visible changes often appear after 8 to 12 weeks, as its poly-L-lactic acid formula takes time to integrate and activate collagen production. Most patients need sessions spaced weeks apart to achieve optimal facial rejuvenation or off-label body contouring results.

Duration of Results

• Lanluma: Results may last up to 2 years, particularly in areas like the buttocks, hips, and thighs, where the product provides deep structural support. The longevity, combined with the ability to treat large body areas, contributes to high patient satisfaction.
• Sculptra: Clinical outcomes typically last between 18 to 24 months, depending on the treated area, skin quality, and the number of sessions. While often used for facial volume restoration, off-label body applications may yield slightly varied durations.

Multiple sessions (usually 2 to 3) are recommended for both fillers to achieve the best possible results. However, Lanluma users frequently report greater satisfaction when treating larger areas like the buttocks or thighs, thanks to its thicker consistency and ability to create smoother, more cohesive volume without visible lumps. 

Cost, Availability, and Regulatory Considerations

Regarding cost and access, both treatments offer unique advantages:

• Sculptra has FDA approval for treating facial volume loss and is widely available in clinics worldwide. Its off-label body use may require more expertise and often involves higher costs due to multiple vials priced roughly between $500 and $800 each, with 2 to 4 vials commonly needed per session.
• Lanluma holds a CE mark in Europe and is approved for facial and body contouring. It is gaining traction particularly in the UK and Australia, favored for high-volume treatments like non-surgical butt lifts. Lanluma vial costs range from $600 to $1,000, depending on location and provider.

Patients should consider these financial and regulatory differences when choosing treatment, alongside clinical advice.

Conclusion

The choice between Lanluma vs. Sculptra is not about which is better universally, but rather which is better suited to the patient’s goals. Sculptra excels at facial rejuvenation, delivering gradual, natural volume restoration, while Lanluma offers versatility in reshaping larger body areas through collagen stimulation.

For patients seeking to smooth hip dips, enhance the buttocks, or sculpt thighs, Lanluma’s formulations may be more appropriate. Conversely, those focused on facial volume and contouring often trust Sculptra’s long-standing clinical track record.

It is crucial to consult a qualified aesthetic provider who can provide tailored advice and help set realistic expectations, especially considering the current lack of scientific studies on body applications of these fillers. With proper guidance, patients can safely achieve their aesthetic goals.

FAQs

1. Can I use Lanluma and Sculptra together?

Yes, in some cases. Some patients use Sculptra for facial enhancement and Lantus for the body. Always consult a trained provider for personalized guidance.

2. Are the results of Lanluma immediate?

No. Like Sculptra, Lanluma works gradually by encouraging collagen production. You’ll begin to notice changes in 6–8 weeks, with full results appearing after a few months.

3. What are the side effects of Lanluma?

Common Lanluma side effects include swelling, redness, tenderness, and small lumps. These are usually temporary. Serious complications are rare with skilled injectors.

4. How many sessions do I need with Lanluma or Sculptra?

Most people need 2–3 sessions spaced 4–6 weeks apart. The number of vials per session varies by area and desired result. Your provider will create a custom plan for you.

References

IMARC Group. Body Contouring Market Size, share, Growth Analysis 2025-33. https://www.imarcgroup.com/body-contouring-market

Amselem M, Fatsea D, Forte R, Hasenöhrl C, Haus A, Saalabian A. Safety and effectiveness results of an innovative injectable poly-L-lactic acid-based collagen stimulator (Lanluma®)-Clinical outcomes at 9 months in a post-market study. J Cosmet Dermatol. 2024;23(12):3893-3902. doi:10.1111/jocd.16527

What is Lanluma. Lanluma. https://lanluma.com/healthcare-professionals/what-is-lanluma/
Ao YJ, Yi Y, Wu GH. Application of PLLA (Poly-L-Lactic acid) for rejuvenation and reproduction of facial cutaneous tissue in aesthetics: A review. Medicine (Baltimore). 2024;103(11):e37506. doi:10.1097/MD.0000000000037506