STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine

STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine is a dedicated lip filler manufactured by Laboratories VIVACY in France. It uses IPN-Like Technology™ and BI-FLEX® rheology and contains 20mg/mL hyaluronic acid with 0.3% lidocaine. It is intended for lip augmentation and perioral volume restoration in licensed aesthetic settings. The STYLAGE® range is CE-marked for use in the EU, subject to local regulatory requirements.

STYLAGE® LIPS PLUS BI-FLEX® with Lidocaine is used for lip augmentation, perioral volume restoration, vermillion border definition, and correction of lip volume loss. Its use depends on patient anatomy, the desired degree of augmentation, tissue characteristics, and practitioner assessment. It should be administered only by trained aesthetic professionals.

The primary difference lies in the hyaluronic acid concentration and structural density. STYLAGE® LIPS contains 18.5mg/g of HA and is designed for subtle, natural enhancement and hydration. STYLAGE® LIPS PLUS contains a higher concentration of 20mg/g of HA, making it more suitable for patients desiring pronounced lip volume, sharp border definition, and structural correction of the perioral area. Additionally, the Lips Plus variant comes packaged as a 2 × 1mL kit.

STYLAGE® products are CE-marked and clinically used in professional aesthetic medicine. For this lip-specific formulation, relevant considerations include IPN-Like Technology™ for cohesivity under lip movement, BI-FLEX® rheology suited to the lip treatment area, and co-formulated lidocaine for procedural comfort. Suitability for a specific patient or indication should be determined by practitioner assessment based on lip anatomy, treatment goals, and clinical objectives.

The STYLAGE® range is CE-marked for use in the EU, but the current US FDA status should be verified before procurement or use. FDA approval for dermal fillers is product- and indication-specific. Practitioners should confirm jurisdiction-specific regulatory status before clinical discussion, procurement, or administration.

Common side effects include swelling, redness, tenderness, bruising at the injection site, pain, itching, or firmness in the lip treatment area. These reactions commonly resolve within a few days. Worsening pain, change in skin color, blanching, livedo, or visual symptoms require urgent clinical evaluation.

Citations

1. Ordynowski Ł. Cross-Linked Hyaluronic Acid for Cleft Lip and Palate Aesthetic Correction: A Preliminary Report. Aesthet Surg J Open Forum. 2022;4:ojac052. Published 2022 Jun 8. doi:10.1093/asjof/ojac052
2. Steenen SA, Bauland CG, van der Lei B, et al. Head-to-head comparison of 4 hyaluronic acid dermal fillers for lip augmentation: A multicenter randomized, quadruple-blind, controlled clinical trial. J Am Acad Dermatol. 2023;88(4):932-935. doi:10.1016/j.jaad.2022.11.012
3. Jain R, Tanawde S, Joshi S, Naik C, Garad A, Chablani D. Advancements in lip augmentation: A scoping review exploring novel techniques. J Cutan Aesthet Surg. 2024;17(3):167-176. doi:10.25259/jcas_144_23

For licensed medical professionals only. This content is for informational purposes only and does not constitute medical advice.