HArmonyCA™

HArmonyCA™ is a hybrid injectable dermal filler that uniquely combines hyaluronic acid (HA) with calcium hydroxyapatite (CaHA) to address volume loss and stimulate collagen production. Developed by Allergan Aesthetics, this dual-effect formulation is designed to provide both immediate volumizing effects and long-lasting skin firmness through endogenous collagen stimulation. The product is indicated for facial soft tissue augmentation, particularly targeting the cheeks, jawline, and chin, where structural support often diminishes with age.

Patients in clinical trials reported high satisfaction, with 91.6% noting an improvement in treated areas and a 4.1/5 satisfaction score. Visible lifting effects can last up to 12 months, and collagen-stimulating benefits may persist for up to 3 years, depending on individual response.

HArmonyCA™ should be administered into the deep dermal or sub-dermal layers by trained professionals. The inclusion of lidocaine reduces pain during the procedure.

• Injection depth: Deep dermal to sub-dermal
  
• Treatment areas: Cheeks, jawline, chin
  
• Session volume: Clinical trials used approx. 7.4 mL for full-face treatment
  
• Pain management: Contains lidocaine for patient comfort
  
• Results onset: Immediate lifting + long-term improvement over months

HArmonyCA™ is indicated for:

• Facial volume loss correction
  
• Structural support restoration
  
• Skin architecture enhancement
  

Contraindications include:

• Allergy to any component, including lidocaine
  
• Active skin infections or inflammatory conditions
  
• Autoimmune disorders affecting the skin
  

Common side effects:

• Erythema
  
• Edema
  
• Pain and tenderness
  
• Itching at the injection site
  

These reactions are typically mild and resolve within 24–48 hours, with swelling subsiding in up to 7 days.

The hybrid filler is composed of:

• Hyaluronic acid (HA): For immediate volume and hydration
  
• Calcium hydroxyapatite (CaHA): For long-term collagen stimulation
  
• Lidocaine: A local anesthetic to minimize injection discomfort

Each HArmonyCA™ package includes:

• 6 syringes totaling 7.5 mL of injectable gel
  
• Individual sterile packaging per syringe
  
• Accompanying product documentation for administration

Yes, like all dermal fillers, it may cause mild, temporary side effects, including:

• Redness
  
• Swelling
  
• Tenderness
  
• Bruising or itching
  
• Rarely, nodules or palpable material, which may require massage
  

Side effects are generally short-lived, resolving in a few days to a week.

To ensure product integrity:

• Store between 2°C to 25°C (36°F to 77°F)
  
• Protect from direct sunlight and freezing
  
• Keep in original packaging until use
  
• Do not reuse syringes or leftover product
  

For best results, always follow storage and usage instructions provided by the manufacturer or healthcare provider.