INTRALINE® M3 PLUS

INTRALINE® M3 PLUS is a monophasic dermal filler designed for correcting medium to deep wrinkles and performing moderate volume enhancement in key facial areas. Developed using monodensified hyaluronic acid (HA) and BDDE crosslinking technology, this filler ensures smooth application, high cohesiveness, and minimal migration post-injection. M3 PLUS contains 24 mg/mL of HA and 3 mg/mL of lidocaine for enhanced comfort, and is particularly suited for treating nasolabial folds, marionette lines, chin augmentation, and lip volumization.

• Treatment Areas: Lips, chin, nasolabial folds, marionette lines
• Ideal Candidate: Patients with moderate volume loss or facial asymmetry
• Injection Level: Lower dermis or upper subcutaneous layer
• Longevity: Results last 6–12 months

INTRALINE® M3 PLUS is designed for precise medium-depth injections and comes prepackaged with dual needles to match the rheological properties of the product. It allows controlled shaping and volumization with long-lasting effects.

• Injection Level: Lower dermis to upper subcutaneous layer
• Technique: Linear threading, fanning, or bolus techniques
• Gel Texture: Medium particle size for optimal spread and support
• Needle Size: 27G (2 needles included)
• Syringe Volume: 1.1 mL prefilled syringe
• Lidocaine: 3 mg/mL to reduce patient discomfort

This filler is suitable for moderate-to-severe wrinkle correction and facial volume restoration, especially in dynamic areas. It provides natural, lasting results without overcorrection.

Indications:

• Nasolabial folds
• Marionette lines
• Lip enhancement
• Chin projection and shaping

Contraindications:

• Hypersensitivity to hyaluronic acid or lidocaine
• History of severe allergies or anaphylaxis
• Active infection or inflammation at the treatment site
• Pregnancy or breastfeeding

Side Effects:

• Common: Swelling, redness, bruising, mild tenderness
• Occasional: Temporary asymmetry, nodules, local irritation
• Rare: Granulomas, hypersensitivity, or vascular occlusion

M3 PLUS is formulated using high-purity, non-animal derived hyaluronic acid via biofermentation, with lidocaine added for analgesia during injection. It is characterized by its monodensified monophasic structure.

• HA Concentration: 24 mg/mL
• Crosslinking Agent: BDDE (<1 μg/mL)
• Form: Monophasic, homogenized gel
• Lidocaine Content: 3 mg/mL
• HA Source: Bacterial fermentation (non-animal origin)

The product is supplied in a sterile blister pack containing all essential components for single-patient use.

• Contents:
  • 1 x 1.1 mL prefilled syringe
  • 2 x 27G needles
• Packaging: CE-certified, sterile, tamper-evident
• Sterilization Method: Moist heat or equivalent validated process

INTRALINE® M3 PLUS is generally well tolerated, with side effects mostly limited to minor injection-related reactions. Serious adverse events are rare but should be promptly addressed.

• Mild Effects: Redness, bruising, swelling, and local discomfort
• Moderate Effects: Temporary nodules or asymmetry
• Severe (rare): Allergic reaction, vascular compromise, granuloma

Proper storage conditions maintain product integrity and efficacy. Follow all guidelines to ensure safe application.

• Storage Temperature: 2–25°C
• Protection: Keep away from sunlight, moisture, and heat
• Shelf Life: Usually 2–3 years from manufacturing date
• Usage Note: Single-use only. Do not reuse or resterilize