NEURAMIS® VOLUME with Lidocaine

NEURAMIS® VOLUME with Lidocaine is a cross-linked hyaluronic acid (HA) dermal filler designed for restoring volume and contour to the face, cheeks, and chin. Developed using SHAPE™ technology (Stabilized Hyaluronic Acid and Purification Enhancement), it provides high volumizing capacity with minimal residual BDDE for improved safety.

This filler contains 20 mg/mL of HA and 0.3% lidocaine, ensuring both effective augmentation and patient comfort during injection. NEURAMIS® VOLUME with Lidocaine is manufactured by Medytox, a global biotech company, and is FDA Drug Master File registered and EDQM certified for superior quality and biocompatibility.

NEURAMIS® VOLUME with Lidocaine is injected into the deep dermis or subcutaneous layer for structural volume enhancement.

Key features:

• Designed for mid-to-deep injection in facial volume-deficient areas
  
• Supplied with Ultra Thin Wall (UTW) needles for smoother injection flow
  

Administration details:

• Use 27G × 1/2” (13 mm) UTW needle
  
• Injection depth: deep dermis to subcutaneous tissue
  
• Recommended for: cheeks, chin, facial contours
  
• Adjust dosage per anatomical area (typically 0.5–1.0 mL per side)
  

Indications:

• Facial volume restoration
  
• Cheek and chin augmentation
  
• Contour enhancement of mid-to-lower face
  
• Treatment of deep facial folds and depressions
  

Contraindications:

• Known hypersensitivity to HA or lidocaine
  
• Presence of skin infections or inflammation
  
• Autoimmune disorders, bleeding disorders
  
• Use during pregnancy or lactation
  

Possible side effects:

• Local: swelling, bruising, pain, erythema
  
• Rare: nodules, hypersensitivity, vascular occlusion
  

Active ingredients:

• Hyaluronic Acid (HA) – 20 mg/mL, cross-linked
  
• Lidocaine hydrochloride – 0.3% for local anesthetic effect
  

Key formulation notes:

• Cross-linked using BDDE, purified through SHAPE™ technology
  
• Endotoxin level: < 0.04 IU/mg
  
• Residual protein: < 0.1%

Each package contains:

• 1 pre-filled syringe of 1.0 mL
  
• 2 × 27G ½” Ultra Thin Wall needles
  
• Product insert with instructions and precautions
  
• Sterile, single-use packaging
  

Yes, as with all injectable fillers, some side effects may occur, typically transient and localized.

Common side effects:

• Swelling, pain, or redness at the injection site
  
• Bruising or tenderness
  

Less common:

• Lumpiness, itching, or sensitivity
  
• Delayed inflammatory response
  

Rare complications:

• Vascular occlusion
  
• Allergic reactions
  
• Infection
  

To ensure product integrity and sterility, proper storage is essential.

Storage instructions:

• Store at 2°C to 25°C
  
• Do not freeze
  
• Protect from direct sunlight and excessive heat
  
• Use the syringe immediately after opening