NITHYA ENDLESS BEAUTY

NITHYA ENDLESS BEAUTY is a sterile, injectable Type I equine collagen treatment designed to rejuvenate the skin by restoring lost collagen and stimulating the natural production of new collagen fibers. Sourced from equine flexor tendons, it is free of telopeptides, gelatin, and allergens—offering a high-purity, biocompatible product with proven safety and efficacy. Upon injection into the dermis, NITHYA activates fibroblasts and promotes neoangiogenesis, resulting in visibly firmer, hydrated, and younger-looking skin.

Backed by more than 50 clinical studies, this minimally invasive biostimulator is suitable for use on the face, neck, décolleté, hands, and body. It is CE-marked and has shown statistically significant improvements in wrinkles, volume loss, and skin texture, with no reported adverse events to date.

NITHYA is reconstituted immediately before injection and administered intradermally or at the dermo-epidermal junction using microdroplet techniques.

Key features:

• Injectable pure equine Type I collagen
  
• Designed for biorevitalization and volume regeneration
  

Protocol overview:

• Reconstitute 70 mg collagen in 5 mL saline (face/neck) or 200 mg in 10 mL (body)
  
• Use 30G needle, inject at 15° angle
  
• Face: ~1.8 mL over 18 points (0.1 mL per point)
  
• Neck: 0.45 mL over 9 points (0.05 mL per point)
  
• Décolleté: 1.1 mL over 11 points (0.1 mL per point)
  
• Hands: 0.5 mL across 10 points (0.05 mL each)
  
• Perform 3 sessions spaced 2–3 weeks apart
  
• Maintenance session: every 6 months
  

Indications:

• Skin biorevitalization for aging or photo-damaged skin
  
• Volume restoration for face, neck, décolleté, hands, and body
  
• Treatment of acne scars, post-traumatic lesions, and skin laxity
  
• Support for collagen regeneration in HIV-related facial lipoatrophy
  

Contraindications:

• Hypersensitivity to collagen
  
• Autoimmune connective tissue diseases
  
• Uncontrolled epilepsy
  
• Pregnancy or breastfeeding
  
• Active skin infections, inflammation, or keloid risk
  
• Use in vascular collagen disorders or bleeding conditions
  

Each vial contains:

• Sterile equine Type I collagen (powder form)
  
• Free of telopeptides, gelatine, and allergenic proteins
  
• Biodegradable and bioabsorbable formulation
  

Reconstitution:

• Face/neck: 70 mg/5 mL saline
  
• Body: 200 mg/10 mL saline
  

Each package includes:

• Sterile vial containing Type I equine collagen powder
  
• Instructions for use (IFU)
  
• The product must be reconstituted before use and is single-use only
  

NITHYA has an excellent safety profile with no documented long-term adverse events. Minor, transient side effects may occur at the injection site.

Possible side effects:

• Mild burning or stinging sensation
  
• Itching, pain, or hematoma
  
• Nodules or skin discoloration
  
• General injection-related side effects
  

No systemic complications or hypersensitivity reactions have been reported in clinical studies.

Storage instructions:

• Store at room temperature (15–25°C)
  
• Keep in original packaging, protected from moisture and light
  
• Do not freeze
  
• Use immediately after reconstitution
  
• Discard any remaining solution