Re N Tox™ 100u

Re N Tox™ 100u is a purified botulinum toxin type A injectable product used to temporarily reduce moderate to severe glabellar lines caused by repeated activity of the corrugator and procerus muscles. Developed by PharmaResearch BIO, Re N Tox™ is known for its high purity (99.6%), confirmed efficacy, and a molecular weight of approximately 927 kDa, which closely matches that of Botox®. The product is supplied as a lyophilized powder in a 100-unit vial and must be reconstituted with preservative-free 0.9% saline before use. It provides visible aesthetic improvement within a few days and results typically last 3 to 4 months per treatment session.

• Active Ingredient: Clostridium botulinum toxin type A
• Form: Freeze-dried powder
• Dose per vial: 100 units
• Duration of effect: ~3–4 months

Re N Tox™ is reconstituted and administered via intramuscular injection using a 30-gauge needle. The standard dosage for glabellar lines is 20 units, distributed across 5 injection points.

• Reconstitution: 2.5 mL of preservative-free 0.9% sodium chloride (yields 4 U per 0.1 mL)
• Dilution range: 1.0 mL (10 U/0.1 mL) to 8.0 mL (1.25 U/0.1 mL)
• Injection sites: 2 points in each corrugator muscle, 1 point in procerus muscle
• Needle size: 30G
• Total standard dose for glabellar lines: 20 units
• Injection volume per site: 0.1 mL
• Duration of effect: 3 to 4 months
• Do not shake or agitate the vial

Re N Tox™ is indicated for the temporary improvement of moderate to severe glabellar lines in adults aged 18 to 65 years. It works by inhibiting acetylcholine release, leading to muscle relaxation and wrinkle reduction.

Indications:

• Moderate to severe glabellar lines
• Aesthetic wrinkle correction in the forehead and frown lines

Contraindications:

• Known allergy to botulinum toxin
• Infection at the injection site
• Neuromuscular disorders (e.g., myasthenia gravis, ALS)
• Pregnancy or breastfeeding

Side Effects:

• Headache, eyelid ptosis, facial asymmetry
• Injection site pain or redness
• Nausea
• Rare: Allergic reactions, muscle weakness

Re N Tox™ is composed of highly purified Clostridium botulinum toxin type A, lyophilized for stability. No preservatives are included in the formulation.

• Active Ingredient: Botulinum toxin type A (100 units/vial)
• Excipients: No preservatives
• Reconstitution solvent: 0.9% sterile saline (not included)

The product is packaged in a sterile vial suitable for single-patient use. It must be reconstituted immediately prior to use.

• 1 vial containing 100 units of freeze-dried Re N Tox™
• Label with space to record reconstitution time and date
• Instructions for dilution and injection technique

Yes, as with all botulinum toxin products, Re N Tox™ may cause both local and systemic side effects, though most are mild and transient.

Common Side Effects:

• Pain or swelling at injection site
• Headache
• Mild bruising
• Localized muscle weakness

Rare but Serious Effects:

• Drooping eyelid (ptosis)
• Difficulty swallowing or speaking
• Allergic reaction
• Generalized muscle weakness

Proper storage ensures product stability and safety. The product should be used immediately after reconstitution.

• Unreconstituted storage: 2°C to 8°C (refrigerated)
• Reconstituted product shelf life: Use within 24 hours
• Do not freeze
• Store in original vial, away from light
• Do not shake – mix gently by rotating