GHK-Cu 50mg

What is GHK-Cu (50mg)?

GHK-Cu (50mg) is a copper-binding tripeptide composed of three amino acids—Glycine, Histidine, and Lysine—complexed with a copper (Cu²⁺) ion. Commonly referred to as a copper peptide, it is classified as a bioactive metal–peptide complex. The peptide sequence is Gly-His-Lys(Cu²⁺), forming a stable coordination structure with copper.

GHK-Cu Identification

• Chemical Formula: C₁₄H₂₁N₆O₄Cu
• Molecular Weight: 401.91 g/mol
• CAS Number: 89030-95-5

This compound has been studied in laboratory models for its role in tissue remodeling, extracellular matrix regulation, and cellular signaling. Research-grade material is typically produced at ≥95% purity, verified by analytical testing. All findings remain investigational.

What are the key features of GHK-Cu (50mg)?

GHK-Cu (50mg) is supplied as a research-grade copper–peptide complex suitable for controlled experimental applications.

• High research-grade purity (≥95% typical analytical standard)
• Supplied as 50 mg lyophilized peptide complex in a sealed vial
• Tripeptide sequence with copper (Cu²⁺) coordination
• Studied in tissue repair and extracellular matrix research
• Stable for approximately 24 months under recommended storage conditions
• For laboratory research use only
• Intended exclusively for in vitro and preclinical investigations

How is GHK-Cu (50mg) synthesized?

GHK-Cu (50mg) is manufactured using solid-phase peptide synthesis (SPPS) to construct the Gly-His-Lys tripeptide backbone. After peptide assembly, copper ions are introduced under controlled conditions to form the copper coordination complex. The resulting compound is purified using high-performance liquid chromatography (HPLC) to achieve high purity. Structural confirmation and molecular weight verification are typically performed using mass spectrometry (MS). The final product is lyophilized to enhance stability during storage and transport.

What is GHK-Cu (50mg) being studied for? What are its possible benefits?

GHK-Cu (50mg) has been studied in laboratory research related to tissue remodeling and cellular repair. Investigations have explored its involvement in:

• Extracellular matrix regulation
• Collagen and elastin research
• Wound healing models
• Skin biology studies
• Hair follicle research models

In experimental settings, GHK-Cu has been investigated for its potential to modulate growth factor activity and gene expression patterns related to tissue maintenance. These possible biological effects remain under investigation and are based on laboratory findings rather than established clinical applications.

How does GHK-Cu (50mg) work in research studies?

In research environments, GHK-Cu (50mg) is being studied for its ability to bind copper and influence cellular signaling pathways. Copper is an essential trace element involved in enzymatic processes, and the peptide complex may help regulate copper availability in experimental systems. GHK-Cu is thought to affect gene expression and protein synthesis related to structural tissue components in laboratory models. It has been associated with the modulation of growth factor pathways and inflammatory signaling in controlled experimental settings. These mechanisms remain investigational.

What dosing information exists for GHK-Cu (50mg)?

Preclinical studies involving GHK-Cu have been conducted primarily in cell culture systems and animal models. In vitro experiments often use nanomolar to micromolar concentrations to evaluate effects on fibroblast activity and collagen-related markers. In animal research, dosing has been reported in micrograms per kilogram (µg/kg), depending on study design and route of administration. Dosing schedules vary widely across research models. There are no established human dosing guidelines for GHK-Cu (50mg), as it is intended exclusively for laboratory research.

How should GHK-Cu (50mg) be stored and handled?

GHK-Cu (50mg) should be stored at 2–8 °C for routine laboratory handling. For long-term preservation, storage at ≤–20 °C is recommended. Protect the product from excessive light and moisture. After reconstitution with sterile laboratory-grade solvent, short-term storage at 2–8 °C is typically advised. Avoid repeated freeze-thaw cycles to maintain structural stability. The approximate shelf life is 24 months when stored under recommended conditions. Standard laboratory protective equipment should be used during handling, and disposal should follow institutional biosafety procedures.

Where can I read more research about GHK-Cu (50mg)?

The following peer-reviewed publications provide background information on GHK-Cu research:

1. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. doi:10.1155/2015/648108
2. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7):1987. Published 2018 Jul 7. doi:10.3390/ijms19071987
3. Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-988. doi:10.1163/156856208784909435
4. Pickart L, Vasquez-Soltero JM, Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sci. 2017;7(2):20. Published 2017 Feb 15. doi:10.3390/brainsci7020020
5. National Center for Biotechnology Information. PubChem Compound Summary for CID 139035031, Copper tripeptide. https://pubchem.ncbi.nlm.nih.gov/compound/Copper-tripeptide.

Compliance Statement

This product is intended for laboratory research use only and is not approved for human or veterinary use.