Rejuran vs Profhilo – Comparing Treatments

Skin rejuvenation treatments have significantly increased in popularity. In 2023, more than 25 million minimally invasive aesthetic procedures were performed in the United States. These treatments, including injectable skin boosters, are highly sought after by individuals seeking non-invasive ways to combat signs of aging.

Among these treatments are Rejuran and Profhilo, two innovative injectables that improve skin quality. Rejuran is made from salmon DNA to promote skin healing, while Profhilo uses high concentrations of hyaluronic acid to deeply hydrate and remodel the skin. Understanding the differences between these two can help you determine the best option for your skin needs.

In this article, we will compare Rejuran vs Profhilo, exploring their benefits, applications, and how they can help you achieve your aesthetic goals.

Key Takeaways

• Rejuran and Profhilo are both popular skin rejuvenation treatments.
• Rejuran is known for its salmon DNA-based formulation, while Profhilo is a high-concentration hyaluronic acid treatment.
• Both treatments offer skin rejuvenation, hydration, and reduction of fine lines and wrinkles.
• Rejuran and Profhilo have different treatment protocols and patient experiences.

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Understanding Rejuran and Profhilo

Rejuran and Profhilo are two advanced injectable treatments designed to enhance skin quality and combat signs of aging.

Rejuran injection, also known as Rejuran skin booster, utilizes salmon DNA to promote skin healing and regeneration. This innovative treatment helps improve skin texture, elasticity, and overall appearance by stimulating collagen production and repairing damaged skin cells.

On the other hand, Profhilo is a unique injectable that contains high concentrations of hyaluronic acid. It deeply hydrates the skin and remodels its structure, providing a smoother and more youthful look. Profhilo works by dispersing evenly across the skin, enhancing hydration and firmness without adding volume, making it an excellent choice for those seeking natural-looking results.

Formulation and Mechanism of Action

Rejuran is formulated with polynucleotides derived from salmon DNA, which helps repair damaged skin and stimulates collagen production. When administered through an injection, the polynucleotides work at the cellular level to promote healing and regeneration. This mechanism improves skin elasticity, firmness, and overall texture over time, making the Rejuran skin booster an excellent choice for anti-aging and skin rejuvenation.

In contrast, Profhilo is composed of high concentrations of pure hyaluronic acid. Unlike traditional fillers, Profhilo isn’t intended for volume enhancement but for deep hydration and tissue remodeling. Once injected, it disperses evenly beneath the skin, attracting moisture and boosting hydration levels. This leads to improved elasticity, smoother texture, and a radiant glow, effectively counteracting skin laxity and dehydration.

Benefits of Rejuran and Profhilo

Rejuran and Profhilo offer unique skincare benefits, such as making skin look younger and healthier. Here’s a closer look at what these treatments can do for your skin:

Skin Rejuvenation

Skin rejuvenation is a major benefit offered by both Rejuran and Profhilo treatments. Rejuran promotes skin healing and rejuvenation through its salmon DNA-derived polynucleotides, which help regenerate skin cells and improve overall texture. This results in younger, healthier-looking skin.

Meanwhile, Profhilo stimulates the production of collagen types I, III, IV, and VII, as well as elastin, leading to significant improvements in skin vitality and freshness.

Hydration and Elasticity

When it comes to enhancing skin hydration and elasticity, Profhilo stands out due to its high concentration of hyaluronic acid, which binds moisture within the skin and boosts elasticity. This treatment also activates collagen and elastin, making the skin appear firmer and well-hydrated.

While contributing to skin hydration, Rejuran focuses more on repairing damaged skin using salmon DNA, which helps smooth skin texture, reduces the appearance of scars, and minimizes pores.

Fine Lines and Wrinkles Reduction

Both Rejuran and Profhilo effectively reduce fine lines and wrinkles, but they do so through different mechanisms. Rejuran utilizes salmon DNA to promote collagen synthesis, which smooths out wrinkles and repairs minor skin imperfections like scars and enlarged pores.

As for Profhilo, it directly targets dry and sagging skin, improving hydration and firmness, which reduces fine lines and visible wrinkles.

Treatment Protocols

For best results, Rejuran and Profhilo treatments follow unique steps. Each procedure focuses on improving skin, but doctors apply it differently.

Rejuran Treatment Protocol

• Initial Consultation: Discuss your skin concerns and determine if Rejuran is the right treatment for you.
• Preparation: The treatment area is cleansed, and a topical numbing cream is applied to minimize discomfort.
• Injection Sessions: Rejuran is injected using fine needles or micro-needles into targeted areas of the skin. Three initial sessions, each spaced four weeks apart, are typically recommended.
• Maintenance: Maintenance sessions are suggested every six to twelve months to sustain the results. Rejuran after care is crucial for achieving optimal outcomes, including gentle cleansing, avoiding strenuous activities, and protecting the skin from sun exposure to minimize irritation and support healing.

Profhilo Treatment Protocol

• Initial Consultation: Assess skin condition and identify areas that would benefit from Profhilo.
• Preparation: The treatment area is cleaned, and a numbing cream may be applied to enhance comfort.
• Injection Sessions: Profhilo is injected into specific points using a precise injection technique to ensure even distribution. Two initial sessions are typically required, spaced four weeks apart.
• Maintenance Treatments: Follow-up treatments are recommended every six months to maintain skin hydration and elasticity.

Patient Experiences and Results

Patients who tried Rejuran and Profhilo shared their stories. They talked about how their skin felt better and looked younger after treatments.

Photo Courtesy of Dr. Aesthetica

Before: The skin appears dull, with signs of aging, such as fine lines, wrinkles, and uneven skin texture, loss of elasticity and volume contribute to a tired, sagging appearance, making the face look older and less vibrant.

After: The skin is visibly smoother, with fine lines and wrinkles reduced, increased firmness, and a more even complexion, which gives the face a refreshed, youthful glow. The overall texture is improved, enhancing facial contours for a more lifted and rejuvenated look.

Photo Courtesy of Pongsak Clinic

Before: Uneven skin tone, enlarged pores, and signs of sun damage make the face appear aged and tired. Facial contours lack definition, and the skin’s overall appearance is less radiant and firm.

After: The complexion is brighter and more uniform, with refined pores and reduced signs of sun damage. Improved elasticity restores natural contouring, giving the face a more defined, youthful appearance, while the skin looks revitalized and healthier.

Conclusion

Choosing between Rejuran and Profhilo ultimately depends on your specific skin concerns and desired outcomes. Both treatments are effective for achieving youthful, rejuvenated skin and reducing the appearance of wrinkles. If your main goal is deep hydration and improved elasticity,

Profhilo may be the ideal choice. On the other hand, if you’re looking to repair scars and enhance skin healing, Rejuran might be better suited to your needs. Consulting with a qualified dermatologist is essential to determine which treatment will best help you achieve your aesthetic goals.

FAQs

1. What are Rejuran and Profhilo treatments?

Rejuran and Profhilo are skin rejuvenation procedures. They use different methods to enhance the look and feel of your skin.

2. How do Rejuran and Profhilo treatments differ?

While both aim to improve skin, they take unique approaches. Rejuran uses polynucleotides, while Profhilo utilizes hyaluronic acid.

3. Which treatment is better: Rejuran or Profhilo?

It’s about something other than better overall; it depends on your specific needs! For instance, if hydration is a priority, you might lean towards Profhilo.

4. Are there any side effects with these treatments?

Like any procedure, there can be side effects, but they’re typically minimal with both Rejuran and Profhilo – things like temporary redness or swelling at the injection site.

References

American Society of Plastic Surgeons. 2023 Plastic surgery statistics. https://www.plasticsurgery.org/news/plastic-surgery-statistics

Bailey, S. H., Cohen, J. L., & Kenkel, J. M. (2011). Etiology, prevention, and treatment of dermal filler complications. Aesthetic Surgery Journal, 31(1), 110–121. https://doi.org/10.1177/1090820X10391083 

CSK Clinics. (n.d.). Profhilo vs. Rejuran: Which is best for your skin? CSK Clinics. https://cskclinics.com/profhilo-vs-rejuran-which-is-best-for-your-skin/