Re N Tox™ 200u

Re N Tox™ 200u is a high-purity botulinum toxin type A formulation manufactured by PharmaResearch BIO. It is designed for the temporary improvement of moderate to severe glabellar lines and other aesthetic or therapeutic applications requiring botulinum toxin. The product contains 200 units of freeze-dried Clostridium botulinum toxin A per vial, with a confirmed purity of 99.6% and a molecular weight of 927 kDa, matching that of Botox®. Re N Tox™ 200u is reconstituted with 0.9% preservative-free saline and injected intramuscularly. It demonstrates equivalent clinical efficacy to Botox® as shown in electromyography studies, with results lasting around 3 to 4 months after injection.

• Formulation: Lyophilized botulinum toxin type A
• Dose per vial: 200 units
• Purity: 99.6%
• Effect duration: 3–4 months
• Manufacturer: PharmaResearch BIO (South Korea)

Re N Tox™ 200u is reconstituted before use and injected into targeted muscles using a 30G needle. The product must be used within 24 hours after reconstitution and kept refrigerated.

• Reconstitution: Mix with 0.9% preservative-free saline
• Standard dilution: 2.5 mL saline yields 4 U per 0.1 mL
• Alternative dilutions:
  
  • 1.0 mL → 10 U per 0.1 mL
  • 2.0 mL → 5 U per 0.1 mL
  • 4.0 mL → 2.5 U per 0.1 mL
  • 8.0 mL → 1.25 U per 0.1 mL
• Needle size: 30G
• Recommended injection volume per site: 0.1 mL
• Use timeframe: Within 24 hours post-reconstitution
• Do not shake or agitate the vial

Re N Tox™ 200u is indicated for the temporary improvement of moderate to severe glabellar lines caused by the activity of the corrugator and procerus muscles. Off-label use may include other facial wrinkles or medical indications under clinical discretion.

Indications:

• Glabellar frown lines (moderate to severe)
• Forehead lines, crow’s feet (off-label aesthetic use by professionals)
• Therapeutic applications may include blepharospasm, hyperhidrosis, or muscle spasticity (where permitted)

Contraindications:

• Hypersensitivity to botulinum toxin
• Active infection at the injection site
• Neuromuscular disorders (e.g., myasthenia gravis, ALS)
• Pregnancy or breastfeeding
• History of allergic reactions to botulinum toxin

Side Effects:

• Injection site pain, redness, or swelling
• Headache
• Eyelid ptosis (drooping)
• Muscle weakness
• Rare: Anaphylaxis, generalized weakness, visual disturbances

Re N Tox™ 200u contains highly purified botulinum toxin type A in a freeze-dried (lyophilized) form. It is free from preservatives and must be reconstituted before use.

• Active ingredient: Clostridium botulinum toxin type A – 200 units per vial
• Excipients: None (preservative-free)
• Diluent: 0.9% sodium chloride solution (not included in the package)
• Molecular weight: ~927 kDa
• Purity: 99.6%

Each unit of Re N Tox™ 200u is supplied in a single-use, sterile vial. The package includes essential product labeling but does not include the diluent or syringes.

• 1 vial containing 200 units of lyophilized toxin
• Sterile glass vial with flip-off cap
• Instructions for dilution and injection
• Label for recording reconstitution time/date

Side effects associated with Re N Tox™ are typically mild and transient, but serious complications may occur if injected incorrectly or in susceptible patients.

Common Side Effects:

• Redness, bruising, or swelling at injection site
• Muscle weakness in the target area
• Localized pain
• Headache

Rare Adverse Effects:

• Eyelid droop (ptosis)
• Allergic reaction or rash
• Generalized weakness or fatigue
• Visual disturbances

Dysphagia or breathing difficulty (if toxin spreads)

Proper storage is critical to preserve the potency and safety of the product.

• Unreconstituted storage: Refrigerate at 2°C to 8°C
• Do not freeze
• Store in original carton away from light
• Reconstituted product must be used within 24 hours
• Keep out of reach of unauthorized personnel