Epithalon 10mg

What is Epithalon?

Epithalon, also known as the Epithalon peptide, is a synthetic tetrapeptide composed of four amino acids: Ala-Glu-Asp-Gly. It has been studied in laboratory settings for its role in cellular regulation, genomic stability, and age-related biochemical processes. Epithalon for research is frequently examined for its potential influence on pathways associated with oxidative balance, metabolic regulation, and intracellular signaling mechanisms. With a molecular weight of approximately 390.34 g/mol, Epithalon is structurally small, making it suitable for studies involving protein interactions, peptide transport, and cellular signaling research models. Laboratory-grade formulations typically feature purities of ≥95%, confirmed through validated analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry. Researchers who purchase Epithalon commonly work with lyophilized vials designed for controlled experimental applications.

Product Specifications

• Product Name: Epithalon
• Synonyms: Epitalon, Epithalone, Epithalamin
• CAS Number: 307297-39-8
• Chemical Formula: C14H22N4O9
• Subscript Format: C₁₄H₂₂N₄O₉
• Molecular Weight:34 g/mol
• Sequence: Ala-Glu-Asp-Gly
• Peptide Length: 4 amino acids (tetrapeptide)

What are the key features of Epithalon?

Epithalon is supplied as a lyophilized powder, ensuring stability during shipping and long-term storage. It is frequently included in studies focusing on cellular senescence, metabolic regulation, oxidative stress response, and gene expression. The Epithalon 10 mg vial format is commonly used in research environments requiring consistent dosing across multiple assays. Key features include:

• ≥ 95% purity, verified through analytical testing
• Lyophilized, laboratory-ready vial configuration
• Synthetic manufacturing for reproducibility
• Investigated for sleep-related and neuroendocrine pathways
• Compatible with standard peptide solvents
• Common in preclinical studies evaluating neurochemical responses
• For laboratory research use only.

How is Epithalon synthesized?

Epithalon is produced using solid-phase peptide synthesis (SPPS), a controlled method that ensures accurate assembly of its four amino acids. SPPS allows consistent replication of the natural peptide sequence, minimizing variance between batches. Once assembled, Epithalon undergoes purification through high-performance liquid chromatography (HPLC) to eliminate incomplete chains and ensure high purity. Final verification is typically performed using mass spectrometry, which confirms molecular weight and structural integrity. Researchers conducting Epithalon for research studies often select synthetically derived peptides because their manufacturing methods are standardized, reproducible, and optimized for analytical reliability.

What is Epithalon being studied for? What are its possible benefits?

Epithalon has been studied for its role in sleep regulation, stress responses, and metabolic function. Research has examined Epithalon in the context of sleep–wake cycle regulation, stress adaptation, and neuroendocrine signaling. These investigational areas remain preliminary and are not yet conclusive. Preclinical literature has explored Epithalon's potential effects on several biological systems, including its involvement in oxidative stress responses, cellular repair mechanisms, endocrine signaling, and metabolic processes. Some experimental models evaluate Epithalon for its potential effects on protein synthesis and energy utilization. The term “Epithalon anti-aging peptide” reflects historical research focus on its sleep-related mechanisms, though no definitive clinical outcomes have been established. All findings remain limited to laboratory research environments.

How does Epithalon work in research studies?

Laboratory models examine how Epithalon may influence cellular signaling molecules and intracellular processes that regulate stress responses and energy balance. These mechanisms remain under investigation and vary depending on the experimental model used. Epithalon is studied for its potential effects on neurotransmitter systems and cellular signaling pathways. Some preclinical studies explore peptide–protein interactions, while others assess potential effects on cellular membrane receptors or neurotransmitter balance. Because Epithalon is a small, synthetic peptide, it is readily incorporated into standard laboratory protocols, making it suitable for experiments investigating general peptide behavior and neurochemical processes in controlled research environments.

What dosing information exists for Epithalon?

Preclinical studies investigating Epithalon employ various concentrations depending on the research model and methodology:

• In vivo murine models: 10–100 µg/kg (micrograms per kilogram body weight)
• In vitro cellular assays: 1–100 µM (micromolar concentrations)

How should Epithalon be stored and handled?

Store in its lyophilized form at –20 °C, protected from light and moisture. This ensures long-term stability and preserves the peptide’s structural integrity. Laboratories often keep vials in airtight, low-humidity conditions to prevent degradation. Upon reconstitution with suitable sterile solvents, Epithalon is generally recommended to be stored at 2–8 °C for short-term use. To maintain consistency across experiments, many laboratories aliquot solutions to prevent repeated freeze–thaw cycles, which can reduce peptide quality. Researchers who purchase Epithalon for research typically follow standard peptide-handling protocols to ensure stability and reliability during study periods.

Where can I read more research about Epithalon?

Researchers can consult a range of peer-reviewed resources to learn more about Epithalon’s structure, biochemical behavior, and experimental applications. Recommended sources include:

1. Khavinson V, Diomede F, Mironova E, et al. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules. 2020;25(3):609. Published 2020 Jan 30. doi:10.3390/molecules25030609
2. Caputi S, Trubiani O, Sinjari B, et al. Effect of short peptides on neuronal differentiation of stem cells. Int J Immunopathol Pharmacol. 2019;33:2058738419828613. doi:10.1177/2058738419828613
3. Khavinson VKh, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003;135(6):590-592. doi:10.1023/a:1025493705728
4. Anisimov VN, Khavinson VKh, Popovich IG, et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. 2003;4(4):193-202. doi:10.1023/a:1025114230714

Compliance Statement

This product is intended for laboratory research use only and is not approved for human or veterinary use.