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FAQ
BOTOX® 50u (onabotulinumtoxinA) is a prescription neurotoxin indicated for the temporary improvement in the appearance of moderate to severe facial lines in adults. It functions by inhibiting the release of acetylcholine at the neuromuscular junction, causing localized muscle relaxation and softening of dynamic wrinkles. The cosmetic formulation is specifically approved for treating glabellar lines, forehead lines, and lateral canthal lines (crow’s feet). BOTOX® Cosmetic has been extensively tested and demonstrated efficacy and safety in clinical trials, with treatment effects typically lasting three to four months.
BOTOX® Cosmetic is administered via intramuscular injection and should be reconstituted with preservative-free 0.9% sodium chloride. Administration must be performed by healthcare professionals trained in facial anatomy.
- Glabellar Lines: 20 Units total (4 Units per injection at 5 sites)
- Lateral Canthal Lines: 24 Units total (4 Units at 3 sites per side)
- Forehead Lines (with glabellar lines): 40 Units total (20 Units forehead, 20 Units glabella)
- Dilution: 1.25 mL diluent to achieve 4 Units per 0.1 mL
- Needle: 30-33 gauge recommended
BOTOX® Cosmetic is approved for the temporary reduction of facial wrinkles resulting from muscle activity in adults.
Indications:
- Moderate to severe glabellar lines
- Moderate to severe crow’s feet
- Moderate to severe forehead lines
Contraindications:
- Hypersensitivity to botulinum toxin
- Infection at the injection site
Side Effects:
- Eyelid ptosis (3%)
- Eyelid edema (1%)
- Headache (9%)
- Brow ptosis (2%)
- Muscle weakness, dry eye, injection site pain
Each 50-unit vial of BOTOX® contains:
- 50 Units of onabotulinumtoxinA
- 0.25 mg Human Albumin
- 0.45 mg Sodium Chloride
- Vacuum-dried powder, preservative-free
Each package of BOTOX® 50u includes:
- One single-dose vial containing 50 Units of vacuum-dried powder
- Tamper-evident packaging with holographic Allergan seal
Yes, BOTOX® can cause localized and systemic side effects. These reactions are typically mild and transient.
Common Side Effects:
- Headache (up to 9%)
- Eyelid ptosis (3%)
- Brow ptosis (2%)
- Eyelid swelling, injection site pain, facial paresis
Rare but serious:
- Dysphagia
- Breathing difficulties
- Allergic reactions (anaphylaxis)
- Generalized muscle weakness
Proper storage is critical to maintaining BOTOX® efficacy and safety.
- Unopened vials: Store at 2°C to 8°C (36°F to 46°F)
- After reconstitution: Use within 24 hours
- Do not freeze reconstituted product
- Discard any remaining solution after use
