XEOMIN®

XEOMIN®  is designed to temporarily improve the look of moderate to severe frown lines between the eyebrows, forehead wrinkles, and crow’s feet around the eyes. It is also approved for medical use in conditions such as cervical dystonia(CD) and blepharospasm.

What Is XEOMIN® Used For?

XEOMIN® has multiple use cases. It temporarily paralyzes and weakens muscles by blocking the release of the neurotransmitter acetylcholine, responsible for muscle contraction.

Here are some of its uses:

Therapeutic Uses

• CD: Treats distorted head position and cervicalgia due to involuntary muscle contractions.
• Upper Limb Spasticity: Reduces muscle stiffness in the elbow, wrist, and fingers by improving motion and function.
• Blepharospasm: Addresses involuntary blinking or eyelid spasms.
• Chronic Sialorrhea: Reduces excessive drooling in conditions like Parkinson’s disease, cerebral palsy, and stroke.

Read our comprehensive article on Xeomin For Migraines.

Cosmetic Uses

• Glabellar Lines: Smooths moderate and severe glaberllar lines between the eyebrows.
• Forehead Lines: Reduces the appearance of horizontal forehead wrinkles.
• Crow’s Feet: Softens the lines around the eyes caused by smiling or squinting.

How to Prepare XEOMIN® for Administration 

Here are the steps that you need to follow to prepare XEOMIN® for administration:

1. Dilute XEOMIN with sterile, preservative-free 0.9% Sodium Chloride Injection, USP. Make sure that you follow the dilution guide below.
2. Use a 20-27 gauge short bevel needle for reconstitution.
3. Clean the vial’s rubber stopper with 70% alcohol before needle insertion.
4. Let the vacuum draw the saline into the vial, then gently add any remaining saline.
5. Mix the solution by carefully swirling and flipping the vial without vigorous shaking.
6. Use reconstituted XEOMIN within 24 hours and store it in the refrigerator at 2°C – 8°C.

Dilution guide for 50-unit vial:

• For 0.25 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 20.0U per 0.1 mL.
• For 0.5 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 10.0U per 0.1 mL.
• For 1 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 5.0U per 0.1 mL.
• For 1.25 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 4.0U per 0.1 mL.
• For 2 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 2.5U per 0.1 mL.
• For 2.5 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 2.0U per 0.1 mL.
• For 4 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 1.25U per 0.1 mL.
• For 5 mL of added diluent (0.9% sodium chloride injection), the resulting concentration will be 1.0U per 0.1 mL.

Read more on the XEOMIN® dosing chart in our dedicated article

Side Effects

XEOMIN® is recognized for its effective treatment for various muscle and gland-related conditions, though it carries the possibility of side effects. 

Commonly, patients may experience minor reactions such as dry mouth, localized pain, or muscle weakness. 

Other typical responses include eye-related discomforts like dry eyes or drooping eyelids, and systemic symptoms such as headaches or body aches.

Rarely, more serious side effects can occur, which may manifest as difficulties with swallowing, speaking, or muscle coordination.

XEOMIN® vs. Competition

As you already know, the botulinum toxin market is overwhelmed with the number of products due to the growing profitability of the sector.

XEOMIN® stands out due to its unique “naked” formulation, free from complex proteins. Compared to Botox, which contains these proteins, XEOMIN® offers a streamlined alternative that reduces the risk of allergic reactions and side effects.

This unique characteristic tips the scales in favor of XEOMIN® for patients and practitioners seeking a more natural option in aesthetic treatments.

Where Can I Buy This Product?

Do you want to improve your practice with XEOMIN®?

Our dedicated team is on hand to navigate you through the process to buy XEOMIN® online, and to make sure that you get access to competitive wholesale prices. 

Whether you’re interested in bulk purchases or want specific information on integrating XEOMIN® into your services, we’re here to provide support and detailed ordering instructions.